trans-1-Iod-2-trifluormethylcyclohexan

Base Information

• Chemical Name: trans-1-Iod-2-trifluormethylcyclohexan
• CAS No.: 103359-79-1
• Molecular Formula: C₇H₁₀F₃I
• Molecular Weight: 278.056
• Mol file: 103359-79-1.mol

Synonyms:

Chemical Property of trans-1-Iod-2-trifluormethylcyclohexan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-1-Iod-2-trifluormethylcyclohexan

There total 3 articles about trans-1-Iod-2-trifluormethylcyclohexan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

iodotrifluoromethane (2314-97-8,263005-66-9) + cyclohexene (110-83-8) → trans-1-Iod-2-trifluormethylcyclohexan (89728-79-0,103359-79-1,103359-80-4) + 1-(trifluoromethyl)-1-cyclohexene (454-55-7)

Guidance literature:

With tris(1,10-phenanthroline)ruthenium(II) dichloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; Inert atmosphere; Irradiation;

DOI:10.1021/jo3022346

Reference yield: 27.0%

(trifluoromethyl)trimethylsilane (81290-20-2) + cyclohexene (110-83-8) → trans-1-Iod-2-trifluormethylcyclohexan (89728-79-0,103359-79-1,103359-80-4) + 1-(trifluoromethyl)-1-cyclohexene (454-55-7)

Guidance literature:

With N-iodo-succinimide; silver(I) acetate; sodium acetate; In dimethyl sulfoxide; at 20 ℃; for 24h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/acs.orglett.9b00332

Reference yield:

iodotrifluoromethane (2314-97-8,263005-66-9) + cyclohexene (110-83-8) → trans-1-Iod-2-trifluormethylcyclohexan (89728-79-0,103359-79-1,103359-80-4) + cis-1-Iod-2-trifluormethylcyclohexan

Guidance literature:

for 96h; Product distribution; Irradiation; The yields, the kind of products depend on the time of the irrad. and/or the temp., and the mol. ratio. Other trifluorometh. agents investigated;

DOI:10.1016/S0022-1139(00)80523-0

upstream raw materials:

iodotrifluoromethane

cyclohexene

(trifluoromethyl)trimethylsilane