Technology Process of (2-benzenesulfonyl-3-methoxy-4,4-dimethylcyclopent-2-enyl)acetonitrile
There total 3 articles about (2-benzenesulfonyl-3-methoxy-4,4-dimethylcyclopent-2-enyl)acetonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tributylphosphine;
In
acetonitrile;
for 3h;
Inert atmosphere;
DOI:10.1021/jo3015769
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 3-chloro-benzenecarboperoxoic acid / water; dichloromethane / 0.75 h / 0 °C / Inert atmosphere
2: tributylphosphine / acetonitrile / 3 h / Inert atmosphere
With
tributylphosphine; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; water; acetonitrile;
DOI:10.1021/jo3015769
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -30 °C / Inert atmosphere
1.2: 1.5 h / -30 - 20 °C / Inert atmosphere
2.1: triethylamine; dimethyl sulfoxide; sulfur trioxide pyridine complex / dichloromethane / 4 h / 0 °C / Inert atmosphere; Heating
3.1: dichloromethane / 9 h / Inert atmosphere
4.1: 3-chloro-benzenecarboperoxoic acid / water; dichloromethane / 0.75 h / 0 °C / Inert atmosphere
5.1: tributylphosphine / acetonitrile / 3 h / Inert atmosphere
With
n-butyllithium; tributylphosphine; sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; hexane; dichloromethane; water; acetonitrile;
3.1: |Wittig Olefination;
DOI:10.1021/jo3015769
