optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone

Base Information

• Chemical Name: optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone
• CAS No.: 860699-97-4
• Molecular Formula: C₂₁H₂₂O₃
• Molecular Weight: 322.404
• Mol file: 860699-97-4.mol

Synonyms:

Chemical Property of optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone

There total 1 articles about optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methylcyclohexanone (583-60-8) + benzil (134-81-6) → optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone (860699-97-4)

Guidance literature:

With sodium methylate;

DOI:10.1021/jo01145a010

Reference yield:

optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone (860699-97-4) → 8-methyl-3,4-diphenyl-5,6,7,8-tetrahydro-cinnoline

Guidance literature:

With hydrazine hydrate; toluene;

DOI:10.1021/ja01156a118

Reference yield:

optically inactive 2-hydroxy-2-(3-methyl-2-oxo-cyclohexyl)-1,2-diphenyl-ethanone (860699-97-4) → 7-methyl-2,3-diphenyl-1H-indole (54879-93-5)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄+H₂O; toluene

2: palladium/charcoal

With palladium on activated charcoal; hydrazine hydrate; toluene;

DOI:10.1021/ja01156a118

upstream raw materials:

2-Methylcyclohexanone

benzil

Downstream raw materials:

7-methyl-2,3-diphenyl-1H-indole