Technology Process of C22H22ClF2N7O
There total 7 articles about C22H22ClF2N7O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-chlorobenzyl bromide;
With
sodium azide;
In
dimethyl sulfoxide;
at 20 ℃;
for 6h;
1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difuorophenyl)-3-(N-methyl-N-propargylamino)-2-propanol;
With
copper(ll) sulfate pentahydrate; L-ascorbic acid sodium salt;
In
water; dimethyl sulfoxide;
at 20 ℃;
for 2h;
DOI:10.1039/c3md20086h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / methanol / 6 h / Reflux
2.1: potassium iodide; potassium carbonate / acetonitrile / 6 h / 20 °C
3.1: sodium azide / dimethyl sulfoxide / 6 h / 20 °C
3.2: 2 h / 20 °C
With
sodium azide; potassium carbonate; triethylamine; potassium iodide;
In
methanol; dimethyl sulfoxide; acetonitrile;
DOI:10.1039/c3md20086h
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: aluminum (III) chloride / 5 h / 50 °C
2.1: sodium hydrogencarbonate / toluene / 5 h / Reflux
3.1: sodium hydroxide / toluene / 3 h / 60 °C
4.1: methanesulfonic acid / 1 h / 0 °C
5.1: triethylamine / methanol / 6 h / Reflux
6.1: potassium iodide; potassium carbonate / acetonitrile / 6 h / 20 °C
7.1: sodium azide / dimethyl sulfoxide / 6 h / 20 °C
7.2: 2 h / 20 °C
With
aluminum (III) chloride; sodium azide; methanesulfonic acid; sodium hydrogencarbonate; potassium carbonate; triethylamine; potassium iodide; sodium hydroxide;
In
methanol; dimethyl sulfoxide; toluene; acetonitrile;
DOI:10.1039/c3md20086h
