2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate

Base Information

• Chemical Name: 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate
• CAS No.: 1333471-54-7
• Molecular Formula: C₂₅H₃₇F₃O₁₃S
• Molecular Weight: 634.622
• Mol file: 1333471-54-7.mol

Synonyms:

Chemical Property of 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate

There total 6 articles about 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

trifluoromethylsulfonic anhydride (358-23-6) + 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenol (1333471-52-5) → 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate (1333471-54-7)

Guidance literature:

With pyridine; In dichloromethane; at -10 ℃; for 1.05h; Inert atmosphere;

DOI:10.1039/c1dt10556f

Reference yield:

4,6-dimethyl-2-methoxymethoxyisophthalic acid dimethyl ester (1333471-42-3) → 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate (1333471-54-7)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 2,2'-azobis(isobutyronitrile) / dichloromethane / 1 h / 25 °C / Inert atmosphere; Irradiation

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

2.2: 0 °C / Inert atmosphere

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 25 °C / Inert atmosphere

4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.58 h / -78 °C / Inert atmosphere

4.2: 0 - 25 °C / Inert atmosphere

5.1: hydrogenchloride; methanol / 2 h / 25 °C / Inert atmosphere

6.1: pyridine / dichloromethane / 1.05 h / -10 °C / Inert atmosphere

With pyridine; hydrogenchloride; methanol; lithium aluminium tetrahydride; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); sodium hydride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane; mineral oil; 4.1: Swern oxidation / 4.2: Swern oxidation;

DOI:10.1039/c1dt10556f

Reference yield:

2-methoxymethoxy-4,6-bis(2,5,8,11-tetraoxadodecyl)isophthalic acid dimethyl ester (1333471-46-7) → 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate (1333471-54-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 25 °C / Inert atmosphere

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.58 h / -78 °C / Inert atmosphere

2.2: 0 - 25 °C / Inert atmosphere

3.1: hydrogenchloride; methanol / 2 h / 25 °C / Inert atmosphere

4.1: pyridine / dichloromethane / 1.05 h / -10 °C / Inert atmosphere

With pyridine; hydrogenchloride; methanol; lithium aluminium tetrahydride; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane; 2.1: Swern oxidation / 2.2: Swern oxidation;

DOI:10.1039/c1dt10556f

upstream raw materials:

trifluoromethylsulfonic anhydride

2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenol

4,6-dimethyl-2-methoxymethoxyisophthalic acid dimethyl ester

4,6-bis(bromomethyl)-2-methoxymethoxyisophthalic acid dimethyl ester

Downstream raw materials:

trans-(2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadecyl)phenyl)chlorobis(triphenylphosphine)palladium