(S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate

Base Information

Chemical Name:(S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate
CAS No.:67436-18-4
Molecular Formula:C₁₅H₂₁NO₄
Molecular Weight:279.336
Hs Code.:
DSSTox Substance ID:DTXSID30454774
Wikidata:Q82276497

Synonyms:Z-Val-OEt;67436-18-4;(S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate;ethyl (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate;(s)-n-cbz-valine ethyl ester;SCHEMBL14595222;DTXSID30454774;MFCD06658546;AKOS022175211;DS-6508;CS-0151937;A867269;(S)-Ethyl 2-(((benZyloxy)carbonyl)amino)-3-methylbutanoate (CbZ-L-Val-OEt)

Suppliers and Price of (S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Z-Val-OEt 95+%
25g
$ 495.00

Crysdot
Z-Val-OEt 95+%
10g
$ 248.00

ChemPep
Z-Val-OEt ≥98%
25g
$ 151.00

ChemPep
Z-Val-OEt ≥98%
100g
$ 305.00

Chemenu
Z-Val-OEt 95%
25g
$ 468.00

Chemenu
Z-Val-OEt 95%
10g
$ 234.00

Chemenu
Z-Val-OEt 95%
5g
$ 153.00

Ambeed
Z-Val-OEt 95+%
25g
$ 159.00

Ambeed
Z-Val-OEt 95+%
5g
$ 49.00

Ambeed
Z-Val-OEt 95+%
1g
$ 14.00

Total 23 raw suppliers

Chemical Property of (S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate

Chemical Property:

Boiling Point:402.8±38.0 °C(Predicted)
PKA:11.00±0.46(Predicted)
Density:1.098±0.06 g/cm3(Predicted)
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:279.14705815
Heavy Atom Count:20
Complexity:311

Purity/Quality:

97% ^*data from raw suppliers

Z-Val-OEt 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CCOC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1

Technology Process of (S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate

There total 3 articles about (S)-Ethyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 64-17-5
ethanol

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 67436-18-4,42998-42-5
N-benzyloxycarbonyl-S-valine methyl ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1021/acs.orglett.1c02769

Reference yield: 76.0%

: 64-17-5
ethanol

: 1149-26-4,1685-33-2,92077-76-4,3588-63-4
N-benzyloxycarbonylvaline

: 1685-33-2
N-[(benzyloxy)carbonyl]-D-valine

: 67436-18-4,42998-42-5
N-benzyloxycarbonyl-S-valine methyl ester

Guidance literature:: industrial papain; at 50 ℃; for 4h; pH 4,5 (citrate buffer, cystein*HCl);
DOI:10.1016/0223-5234(87)90273-X

Reference yield:

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 541-41-3
chloroformic acid ethyl ester

: 67436-18-4,42998-42-5
N-benzyloxycarbonyl-S-valine methyl ester

Guidance literature:: With dmap; triethylamine; Yield given. Multistep reaction; 1.) CH₂Cl₂, 0 deg C, 10 min, 2.) 0 deg C, 30 min;
DOI:10.1021/jo00205a004