ethyl 5-fluoroorotic acid

Base Information

Chemical Name:ethyl 5-fluoroorotic acid
CAS No.:132214-26-7
Molecular Formula:C₇H₇FN₂O₄
Molecular Weight:202.142
Hs Code.:

Synonyms:

Suppliers and Price of ethyl 5-fluoroorotic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl5-fluoro-2,6-dihydroxypyrimidine-4-carboxylate 97%
1g
$ 465.00

AK Scientific
Ethyl5-fluoroorotate
1g
$ 802.00

Total 2 raw suppliers

Chemical Property of ethyl 5-fluoroorotic acid

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Ethyl5-fluoro-2,6-dihydroxypyrimidine-4-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 5-fluoroorotic acid

There total 1 articles about ethyl 5-fluoroorotic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 703-95-7
5-fluoroorotic acid

: 75-03-6
ethyl iodide

: 132214-26-7
ethyl 5-fluoroorotic acid

Guidance literature:: 5-fluoroorotic acid; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; for 0.5h;

ethyl iodide; In N,N-dimethyl-formamide; at 60 ℃; for 2h;

Reference yield: 93.0%

: 132214-26-7
ethyl 5-fluoroorotic acid

: 1266238-63-4
ethyl 2,6-dichloro-5-fluoropyrimidine-4-carboxylate

Guidance literature:: ethyl 5-fluoroorotic acid; With N,N-diethylaniline; trichlorophosphate; at 90 ℃; for 4h;

With sodium hydrogencarbonate; In water; pH=8;

Reference yield:

: 132214-26-7
ethyl 5-fluoroorotic acid

: 1266238-52-1
(S)-5'-fluoro-2-[2-(4-fluoro-phenyl)-morpholin-4-yl]-1-methyl-1H-[4,4']bipyrimidinyl-6-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: N,N-diethylaniline; trichlorophosphate / 4 h / 90 °C

1.2: pH 8

2.1: triethylamine; hydrogen / 5% Pd(II)/C(eggshell) / tetrahydrofuran / 3 h

3.1: lithium hexamethyldisilazane / hexane; tetrahydrofuran / -80 °C

3.2: 3 h / -80 - 20 °C

4.1: ethanol / 14 h / 60 - 90 °C

5.1: trichlorophosphate / N,N-dimethyl-formamide; 1,2-dichloro-ethane / 1 h / 0 - 40 °C

6.1: triethylamine / tetrahydrofuran / 8 h / 20 °C

With hydrogen; triethylamine; N,N-diethylaniline; lithium hexamethyldisilazane; trichlorophosphate; 5% Pd(II)/C(eggshell); In tetrahydrofuran; ethanol; hexane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;