2-Methoxyhexadecanoic acid methyl ester

Base Information

• Chemical Name: 2-Methoxyhexadecanoic acid methyl ester
• CAS No.: 16725-36-3
• Molecular Formula: C₁₈H₃₆O₃
• Molecular Weight: 300.482
• Mol file: 16725-36-3.mol

Synonyms:

Chemical Property of 2-Methoxyhexadecanoic acid methyl ester

Chemical Property:

Purity/Quality:

2-METHOXY-HEXADECYLCARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methoxyhexadecanoic acid methyl ester

There total 10 articles about 2-Methoxyhexadecanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

methyl (R)-2-hydroxyhexadecanoate (16742-51-1,78330-57-1,89301-98-4,36451-47-5) + methyl iodide (74-88-4) → methyl (R)-2-methoxyhexadecanoate (16725-36-3)

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

DOI:10.1016/S0957-4166(99)00404-8

Reference yield:

DL-2-hydroxydecanoic acid (5393-81-7,37639-46-6) + p-toluenesulfonyl chloride (98-59-9) + 2-methoxy-hexadecan-1-ol (16725-37-4) + (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol (100-79-8,36543-79-0) → methyl 2-methoxyhexadecanoate (16725-36-3)

Guidance literature:

borone trifluoride; In pyridine;

Reference yield:

methanol (67-56-1) + 2-hydroxypalmitic acid (764-67-0,10067-06-8) → methyl 2-methoxyhexadecanoate (16725-36-3)

Guidance literature:

With potassium hydroxide; at 80 ℃; for 0.0833333h;

DOI:10.1021/jf800647w

upstream raw materials:

methyl (R)-2-hydroxyhexadecanoate

methyl iodide

2-hydroxypalmitic acid

methyl 2-bromohexadecanoate

Downstream raw materials:

methyl 2-hydroxypalmitate

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