9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione

Base Information

• Chemical Name: 9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione
• CAS No.: 130593-37-2
• Molecular Formula: C₂₃H₁₆N₆O₃
• Molecular Weight: 424.418
• Mol file: 130593-37-2.mol

Synonyms:

Chemical Property of 9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione

There total 3 articles about 9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

oxalyl dichloride (79-37-8) + 6-amino-1,4,5,6-tetrahydro-5-imino-3-methyl-1,4-diphenylpyrazolo<4',3':5,6>pyrano<2,3-d>pyrimidine (130593-32-7) → 9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione (130593-37-2)

Guidance literature:

In benzene; for 10h; Heating;

DOI:10.1055/s-1990-26989

Reference yield:

6-amino-1,4-dihydro-3-methyl-1,4-diphenylpyrano[2,3-c]pyrazole-5-carbonitrile (53316-57-7) → 9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione (130593-37-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / acetic anhydride / 5 h / Heating

2: 41 percent / hydrazine hydrate / benzene; H₂O / 0.75 h

3: 71 percent / benzene / 10 h / Heating

With acetic anhydride; hydrazine hydrate; In water; benzene;

DOI:10.1055/s-1990-26989

Reference yield:

ethyl N-(5-cyano-1,4-dihydro-3-methyl-1,4-diphenylpyrano<2,3-c>pyrazol-6-yl)methanimidate (130593-31-6) → 9,12-dihydro-11-methyl-9,12-diphenyl-2H-pyrazolo<4'',3'':5',6'>pyrano<2',3':4,5>pyrimido<1,6-b><1,2,4>triazine-2,3(4H)-dione (130593-37-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 41 percent / hydrazine hydrate / benzene; H₂O / 0.75 h

2: 71 percent / benzene / 10 h / Heating

With hydrazine hydrate; In water; benzene;

DOI:10.1055/s-1990-26989

upstream raw materials:

oxalyl dichloride

6-amino-1,4,5,6-tetrahydro-5-imino-3-methyl-1,4-diphenylpyrazolo<4',3':5,6>pyrano<2,3-d>pyrimidine

6-amino-1,4-dihydro-3-methyl-1,4-diphenylpyrano[2,3-c]pyrazole-5-carbonitrile

ethyl N-(5-cyano-1,4-dihydro-3-methyl-1,4-diphenylpyrano<2,3-c>pyrazol-6-yl)methanimidate