Welcome to LookChem.com Sign In|Join Free
  • or
6-AMINO-3-METHYL-1,4-DIPHENYL-1,4-DIHYDRO-PYRANO[2,3-C]PYRAZOLE-5-CARBONITRILE is a chemical compound with potential pharmaceutical applications. It is a derivative of pyrazole, containing a carbonitrile group and an amino group. 6-AMINO-3-METHYL-1,4-DIPHENYL-1,4-DIHYDRO-PYRANO[2,3-C]PYRAZOLE-5-CARBONITRILE's structure includes a pyrano ring system, which may contribute to its biological activity. This chemical may have potential uses in medicinal chemistry, particularly in the development of new drugs for various diseases or conditions. Its unique structure and functional groups make it an interesting target for further research and exploration in the field of drug discovery.

53316-57-7

Post Buying Request

53316-57-7 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

53316-57-7 Usage

Uses

Used in Pharmaceutical Industry:
6-AMINO-3-METHYL-1,4-DIPHENYL-1,4-DIHYDRO-PYRANO[2,3-C]PYRAZOLE-5-CARBONITRILE is used as a chemical intermediate for the synthesis of new drugs, due to its unique structure and functional groups that may contribute to the development of novel therapeutic agents.
Used in Drug Discovery Research:
6-AMINO-3-METHYL-1,4-DIPHENYL-1,4-DIHYDRO-PYRANO[2,3-C]PYRAZOLE-5-CARBONITRILE is used as a target compound for further research and exploration in the field of drug discovery, as its pyrano ring system and functional groups may offer new avenues for the development of innovative pharmaceuticals to treat various diseases or conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 53316-57-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,3,1 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 53316-57:
(7*5)+(6*3)+(5*3)+(4*1)+(3*6)+(2*5)+(1*7)=107
107 % 10 = 7
So 53316-57-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H16N4O/c1-13-17-18(14-8-4-2-5-9-14)16(12-21)19(22)25-20(17)24(23-13)15-10-6-3-7-11-15/h2-11,18H,22H2,1H3/t18-/m1/s1

53316-57-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-amino-3-methyl-1,4-diphenyl-4H-pyrano[2,3-c]pyrazole-5-carbonitrile

1.2 Other means of identification

Product number -
Other names 6-amino-5-cyano-1,4-dihydro-3-methyl-1,4-diphenylpyrano<2,3-c>pyrazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53316-57-7 SDS

53316-57-7Relevant academic research and scientific papers

A facile one pot synthesis of pyrano[2,3-c]pyrazole derivatives under microwave irradiation

Zhou, Jian-Feng,Tu, Shu-Jiang,Zhu, Hui-Qin,Zhi, San-Jun

, p. 3363 - 3366 (2002)

A series of substituted pyrano[2,3-c]pyrazole derivatives were synthesized by the one pot reaction of aromatic aldehydes, malononitrile and 3-methyl-1-phenyl-2-pyrazolin-5-one under microwave irradiation in good yields.

HClO4-sio2 nanoparticles: An efficient and versatile catalyst for synthesis of 1,4-dihydropyrano[2,3-c]pyrazoles

Sadeghi, Bahareh,Shirkhani, Mona,Hassanabadi, Alireza

, p. 112 - 114 (2015)

The reaction between aromatic aldehydes, malononitrile and 3-methyl-1-phenyl-2-pyrazoline-5-one catalysed by silica supported perchloric acid nanoparticles (HClO4-sio2 nanoparticles) in solvent H2O under reflux provided a

Catalyst-free UV365-assisted synthesis of pyran annulated heterocyclic scaffolds and evaluation of their antibacterial activities

Dutta, Arup,Rahman, Noimur,Kumar, John Elisa,Rabha, Jintu,Phukan, Tridip,Nongkhlaw, Rishanlang

supporting information, p. 263 - 278 (2020/11/03)

A convenient and eco-friendly, one-pot synthetic protocol for pharmaceutically important pyran-based heterocyclic compounds is repeated herein. The reactions were carried out at room temperature in a water–ethanol solvent mixture under direct irradiation

Zn (II)-Schiff base covalently anchored to CaO@SiO2: A hybrid nanocatalyst for green synthesis of 4H-pyrans

Sameri, Fatemeh,Bodaghifard, Mohammad Ali,Mobinikhaledi, Akbar

, (2021/08/03)

In this study, the Zn (II)-Schiff base covalently anchored onto the surface of CaO@SiO2 nanoparticles. The structure of this hybrid nanomaterial (CaO@SiO2-NH2-Sal-Zn) was characterized using the analytical techniques such

Tungstic acid (H4WO5) immobilized on magnetic-based zirconium amino acid metal–organic framework: An efficient heterogeneous Br?nsted acid catalyst for l-(4-phenyl)-2,4-dihydropyrano[2,3c]pyrazole derivatives preparation

Khademi, Shima,Zahmatkesh, Saeed,Aghili, Alireza,Badri, Rashid

, (2021/02/12)

A new magnetic nanocatalyst based on the immobilization of tungstic acid onto new design robust, cost-effective, green, and scalable zirconium-L-aspartate amino acid metal–organic framework (MOF)-grafted L-(+)-tartaric acid stabilized magnetite nanopartic

Sugarcane Bagasse Ash-Based Silica-Supported Boric Acid (SBA-SiO2-H3BO3): A Versatile and Reusable Catalyst for the Synthesis of 1,4Dihydropyrano[2,3c]pyrazole Derivatives

Kumar, A.,Pandey, A. K.,Shrivastava, S. C.

, p. 653 - 660 (2021/06/02)

Abstract: A simple, green, and efficient protocol has been developed for the synthesis of biologically active 1,4dihydropyrano[2,3c]pyrazole derivatives via one-pot four-component reaction of various substituted benzaldehydes, hydrazine hydrate or phenylh

Synthesis and biological activities of some new phosphorus compounds containing pyranopyrazole moiety

Abdel-Monem, Wafaa R.,Abed-Kariem, Somaia M.,Alfaifi, Mohammad Y.,Ali, Tarik E.,Assiri, Mohammed A.,EL-Edfawy, Somaya M.,El-Shaaer, Hafez M.,Elbehairi, Serag Eldin I.,Hassanin, Noha M.,Shati, Ali A.

, p. 1119 - 1137 (2021/06/21)

A simple method for construction of functionalized pyranopyrazoles containing phosphoramide and phosphonate groups via one-pot reaction was achieved. The methodology depended on the reaction of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3-c]pyrazol

Synthesis and in vitro antimicrobial, antioxidant, and antiproliferative activities of some new pyrano[2,3-c]pyrazoles containing 1,2-azaphospholes, 1,3,2-diazaphosphinines and phosphonate moieties

Ali, Tarik E.,Assiri, Mohammed A.,El-Shaaer, Hafez M.,Abdel-Kariem, Somaia M.,Abdel-Monem, Wafaa R.,El-Edfawy, Somaya M.,Hassanin, Noha M.,Shati, Ali A.,Alfaifi, Mohammad Y.,Elbehairi, Serag Eldin I.

supporting information, p. 2478 - 2497 (2021/06/30)

New 1,2-azaphosphole, 1,3,2-diazaphosphinine, and phosphonate derivatives containing pyrano[2,3-c]pyrazole moiety were achieved. The synthetic pathways depended on the reaction of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile with some phosphorus reagents such as diethyl phosphite, phosphorus sulfides, and phenyl phosphorus halides under different conditions. Compounds 6 and 7 recorded potent antibacterial and antifungal activities with lower toxicity, while compounds 4 and 6 displayed promising antioxidative properties. Further, compounds 4 and 9 exhibited potent cytotoxic effects against MCF-7, HepG-2, and HCT-116 cancer cells. The early apoptotic cell death was observed by the compounds in all types of the treated cells. Compounds 3, 5, 7, 10, and 14 recorded low to moderate percentages of necrosis and late apoptosis toward all treated cells.

Synthesis, characterization and application of Fe3O4@SiO2@CPTMO@DEA-SO3H nanoparticles supported on bentonite nanoclay as a magnetic catalyst for the synthesis of 1,4-dihydropyrano[2,3-c]pyrazoles

Eftekhari far, Behrouz,Nasr-Esfahani, Masoud

, (2020/01/25)

Fe3O4 nanoparticles were prepared and decorated on the surface of nanobentonite (NB), and subsequently modified by the organic and inorganic linkers and then sulfonic acid immobilization on the nanoparticles. The NB-Fe3Os

Sulfonic acid-functionalized Fe3O4-supported magnetized graphene oxide quantum dots: A novel organic-inorganic nanocomposite as an efficient and recyclable nanocatalyst for the synthesis of dihydropyrano[2,3-c]pyrazole and 4H-chromen

Khaleghi Abbasabadi, Masoud,Azarifar, Davood,Esmaili Zand, Hamid Reza

, (2020/10/02)

In this research, the main emphasis has been focused on the preparation of a novel Fe3O4-supported propane-1-sulfonic acid-grafted graphene oxide quantum dots (Fe3O4@GOQD-O-(propane-1-sulfonic acid)) that it was

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 53316-57-7