C₁₆H₂₆N₆O₆

Base Information

• Chemical Name: C₁₆H₂₆N₆O₆
• CAS No.: 847647-19-2
• Molecular Formula: C₁₆H₂₆N₆O₆
• Molecular Weight: 398.419
• Mol file: 847647-19-2.mol

Synonyms:

Chemical Property of C₁₆H₂₆N₆O₆

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₁₆H₂₆N₆O₆

There total 3 articles about C₁₆H₂₆N₆O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

2-methoxyethyl methanesulfonate (16427-44-4) + adenosine-2-amine (2096-10-8) → 3'-O-methoxyethyl-2,6-diaminopurine riboside (256224-02-9) + C16H26N6O6 (847647-19-2) + 2'-O-(2-methoxyethyl)-2,6-diaminopurine riboside (256224-13-2)

Guidance literature:

2-methoxyethyl methanesulfonate; adenosine-2-amine; With sodium hydride; lithium bromide; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 50 - 52 ℃; for 3h;

2-methoxyethyl methanesulfonate; With potassium hydroxide; In dimethyl sulfoxide; for 18h; Further stages.;

DOI:10.1080/15257770701528180

Reference yield: 45.0%

2-Bromoethyl methyl ether (6482-24-2) + adenosine-2-amine (2096-10-8) → 3'-O-methoxyethyl-2,6-diaminopurine riboside (256224-02-9) + C16H26N6O6 (847647-19-2) + C19H32N6O7 + 2'-O-(2-methoxyethyl)-2,6-diaminopurine riboside (256224-13-2)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 6h;

DOI:10.1080/15257770802271748

Reference yield:

2-Bromoethyl methyl ether (6482-24-2) + adenosine-2-amine (2096-10-8) → 3'-O-methoxyethyl-2,6-diaminopurine riboside (256224-02-9) + C16H26N6O6 (847647-19-2) + 2'-O-(2-methoxyethyl)-2,6-diaminopurine riboside (256224-13-2)

Guidance literature:

adenosine-2-amine; With lithium hydroxide monohydrate; In dimethyl sulfoxide; at 20 - 35 ℃; for 0.5h; Inert atmosphere; Large scale;

2-Bromoethyl methyl ether; In dimethyl sulfoxide; at 15 - 35 ℃; for 19h; Reagent/catalyst; Inert atmosphere; Large scale;

DOI:10.1021/acs.oprd.0c00261

upstream raw materials:

2-methoxyethyl methanesulfonate

adenosine-2-amine

2-Bromoethyl methyl ether