2-Ethenyl-6-methylpyrazine

Base Information

• Chemical Name: 2-Ethenyl-6-methylpyrazine
• CAS No.: 13925-09-2
• Molecular Formula: C7H8N2
• Molecular Weight: 120.154
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID70930406
• Nikkaji Number: J101.077H
• Wikidata: Q82905761
• Mol file: 13925-09-2.mol

Synonyms:2-Ethenyl-6-methylpyrazine;13925-09-2;Pyrazine, 2-ethenyl-6-methyl-;2-Methyl-6-vinylpyrazine;Pyrazine, 2-methyl-6-vinyl-;2-Methyl-6-vinyl-pyrazine;2-ethenyl-6-methyl pyrazine;6-methyl-2-vinylpyrazine;2-Vinyl-6-methylpyrazine;SCHEMBL5212754;DTXSID70930406;CHEBI:184348;BS-52425;E84653;EN300-263260

Chemical Property of 2-Ethenyl-6-methylpyrazine

Chemical Property:

• Vapor Pressure: 1.78mmHg at 25°C
• Melting Point: 74-75 °C
• Boiling Point: 172.4oC at 760 mmHg
• PKA: 1.29±0.10(Predicted)
• Flash Point: 63.7oC
• PSA: 25.78000
• Density: 1.017g/cm3
• LogP: 1.42800
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 120.068748264
• Heavy Atom Count: 9
• Complexity: 101

Purity/Quality:

99%, ^*data from raw suppliers

2-Methyl-6-vinyl-pyrazine(~1%Hydroquinoneasstabilizer) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN=CC(=N1)C=C
• Uses: 2-Methyl-6-vinyl-pyrazine can be found in the aroma of beef muscle, popcorn, coffee, and malted barley. It can also be utilized to analyze the thermal behaviour of pyridine esters.

Technology Process of 2-Ethenyl-6-methylpyrazine

There total 6 articles about 2-Ethenyl-6-methylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + (6-methyl-2-pyrazinylmethyl)triphenylphosphonium chloride → 2-Methyl-6-vinyl-pyrazine (13925-09-2)

Guidance literature:

With sodium carbonate; In dichloromethane; water; for 6h;

Reference yield: 38.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,6-dimethylpyrazine (108-50-9) → 2-Methyl-6-vinyl-pyrazine (13925-09-2)

Guidance literature:

With N,N-dimethylammonium chloride; In water; at 100 ℃; for 2h; Microwave irradiation;

DOI:10.3390/molecules14062160

Reference yield:

alpha-D-glucopyranose (492-62-6) + L-lysine (56-87-1,3506-25-0) + glycine (56-40-6,18875-39-3,25718-94-9) → 1,4-pyrazine (290-37-9) + 2,3-dimethylpyrazine (5910-89-4) + 2-ethylpyrazine (13925-00-3) + 2-ethyl-3,6-dimethylpyrazine (13360-65-1) + 2,3,5-trimethyl-6-ethylpyrazine (17398-16-2) + 2-ethyl-3,5-dimethylpyrazine (13925-07-0) + 2-Methyl-6-vinyl-pyrazine (13925-09-2) + 2-Methyl-5-vinyl-pyrazine (13925-08-1) + 2-ethyl-5-methypyrazine (13360-64-0) + 5-ethyl-2,3-dimethylpyrazine (15707-34-3)

Guidance literature:

at 130 ℃; for 2h;

DOI:10.1021/jf301315b

upstream raw materials:

formaldehyd

2,6-dimethylpyrazine

alpha-D-glucopyranose

L-lysine

Refernces

• 1、 Robledo, Norma,Escalante, Jaime,Arzuffi, Rene. "Extraction with SPME and synthesis of 2-methyl-6- vinylpyrazine by a 'One Pot' reaction using microwaves". experimental part. p. 2160 - 2166. Retrieved 2009/10/10.
• 2、 Goldman,Seibl,Flament,Gautschi,Winter,Willhalm,Stoll. "Research on the aromas. On the aroma of coffee. II. Pyrazines and pyridines". . p. 694 - 705. Retrieved 2007/10/04.