AKOS BBS-00006129

Base Information

• Chemical Name: AKOS BBS-00006129
• CAS No.: 139276-16-7
• Molecular Formula: C15H10O3
• Molecular Weight: 238.243
• Mol file: 139276-16-7.mol

Synonyms:(Z)-2-phenylmethylene-5-hydroxy-3(2H)-benzofuranone;6-hydroxy-2-[phenylmethylene]-3(2H)-benzofuranone;6-hydroxyaurone;2-benzylidene-6-hydroxy-benzofuran-3-one;6-Hydroxy-2-[1-phenyl-meth-(Z)-ylidene]-benzofuran-3-one;6-hydroxy-2-(phenylmethylene)-3(2H)-benzofuranone;(Z)-2-benzylidene-6-hydroxybenzofuran-3(2H)-one;

Chemical Property of AKOS BBS-00006129

Chemical Property:

• PSA: 46.53000
• LogP: 3.00840

Purity/Quality:

98%min ^*data from raw suppliers

(2Z)-2-Benzylidene-6-hydroxy-1-benzofuran-3(2H)-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of AKOS BBS-00006129

There total 8 articles about AKOS BBS-00006129 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

6-hydroxybenzofuran-3-one (6272-26-0) + benzaldehyde (100-52-7) → (Z)-2-phenylmethylene-5-hydroxy-3(2H)-benzofuranone (139276-16-7)

Guidance literature:

With potassium hydroxide; In water; at 20 ℃; for 4h;

DOI:10.1016/j.ejmech.2014.04.076

Reference yield: 98.8%

2-chloro-1-(2,4-dihydroxyphenyl)ethanone (25015-92-3) + benzaldehyde (100-52-7) → (Z)-2-phenylmethylene-5-hydroxy-3(2H)-benzofuranone (139276-16-7)

Guidance literature:

With potassium hydroxide; In methanol; water; at 20 ℃;

DOI:10.1002/jhet.2497

Reference yield: 86.0%

3-oxo-2,3-dihydrobenzofuran-6-yl acetate (90921-05-4) + benzaldehyde (100-52-7) → (Z)-2-phenylmethylene-5-hydroxy-3(2H)-benzofuranone (139276-16-7)

Guidance literature:

With aluminum oxide; In dichloromethane; for 72h; Ambient temperature;

DOI:10.1016/S0040-4039(00)61093-6

upstream raw materials:

benzofuran-3,6-diol

benzaldehyde

2-chloro-1-(2,4-dihydroxyphenyl)ethanone

6-hydroxybenzofuran-3-one

Downstream raw materials:

(Z)-6-methoxyaurone

2-Benzyl-6-methoxy-cumaranon

2-benzylidene-6-hydroxy-7-((4-methylpiperazin-1-yl)methyl)benzofuran-3(2H)-one

(2Z)-2-benzylidene-6-hydroxy-7-(piperidin-1-ylmethyl)-1-benzofuran-3(2H)-one