Technology Process of C26H21N5O2S
There total 8 articles about C26H21N5O2S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
water; dimethyl sulfoxide;
at 20 ℃;
Combinatorial reaction / High throughput screening (HTS);
DOI:10.1021/jm300837y
- Guidance literature:
-
Multi-step reaction with 4 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine / 18 h / 20 °C
2: sodium hydroxide; water / methanol / 5 h / 0 - 20 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 24 h / 20 °C
4: copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; sodium L-ascorbate / water; dimethyl sulfoxide / 20 °C / Combinatorial reaction / High throughput screening (HTS)
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; water; benzotriazol-1-ol; copper(II) sulfate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; diethylamine; sodium hydroxide; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
methanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
1: |Sonogashira Cross-Coupling;
DOI:10.1021/jm300837y
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydroxide; water / methanol / 5 h / 0 - 20 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 24 h / 20 °C
3: copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; sodium L-ascorbate / water; dimethyl sulfoxide / 20 °C / Combinatorial reaction / High throughput screening (HTS)
With
water; benzotriazol-1-ol; copper(II) sulfate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
methanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/jm300837y