Diethyl {[hydroxy(phenyl)amino]methylidene}propanedioate

Base Information

• Chemical Name: Diethyl {[hydroxy(phenyl)amino]methylidene}propanedioate
• CAS No.: 4504-11-4
• Molecular Formula: C14H17 N O5
• Molecular Weight: 279.293
• NSC Number: 56388
• DSSTox Substance ID: DTXSID00288528
• Mol file: 4504-11-4.mol

Synonyms:4504-11-4;NSC56388;DTXSID00288528;NSC-56388;diethyl {[hydroxy(phenyl)amino]methylidene}propanedioate

Chemical Property of Diethyl {[hydroxy(phenyl)amino]methylidene}propanedioate

Chemical Property:

• Vapor Pressure: 1.19E-05mmHg at 25°C
• Boiling Point: 354.9°C at 760 mmHg
• Flash Point: 168.4°C
• Density: 1.244g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 279.11067264
• Heavy Atom Count: 20
• Complexity: 341

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(=CN(C1=CC=CC=C1)O)C(=O)OCC

Technology Process of Diethyl {[hydroxy(phenyl)amino]methylidene}propanedioate

There total 5 articles about Diethyl {[hydroxy(phenyl)amino]methylidene}propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 2-(hydroxymethylene)malonate (20734-18-3) + N-Phenylhydroxylamine (100-65-2) → (N-hydroxy-anilinomethylene)-malonic acid diethyl ester (4504-11-4)

Guidance literature:

With methanol;

Reference yield:

diethyl methylenemalonate (3377-20-6,30329-60-3) + Nitrosobenzene (586-96-9) → (N-hydroxy-anilinomethylene)-malonic acid diethyl ester (4504-11-4)

Guidance literature:

With chloroform;

Reference yield:

diethyl methylenemalonate (3377-20-6,30329-60-3) + chloroform (67-66-3,8013-54-5) + Nitrosobenzene (586-96-9) → (N-hydroxy-anilinomethylene)-malonic acid diethyl ester (4504-11-4)

Guidance literature:

reagiert analog mit 4-Chlor-1-nitrosobenzol;

upstream raw materials:

diethyl 2-(hydroxymethylene)malonate

N-Phenylhydroxylamine

diethyl methylenemalonate

chloroform

Downstream raw materials:

diethyl phenylcarbamoylmalonate

Nitrosobenzene