Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester

Base Information

• Chemical Name: Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester
• CAS No.: 209053-03-2
• Molecular Formula: C₄₃H₇₀N₂O₇
• Molecular Weight: 727.038

Synonyms:

Chemical Property of Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester

There total 1 articles about Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylhydrazine (100-63-0) + Acetic acid (1R,7R,12R)-7,12-dihydroxy-1-(5-hydroxy-5-methyl-2-oxo-2,5-dihydro-furan-3-ylmethyl)-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-dodecyl ester (209116-40-5) → Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester (209053-03-2)

Guidance literature:

In ethanol; for 2h; Heating;

DOI:10.1055/s-2006-957452

Reference yield:

R-(+)-α-trifluoromethyl-α-methoxy-phenylacetic acid (20445-31-2) + Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester (209053-03-2) → C73H91F9N2O13

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 6h; Ambient temperature;

DOI:10.1055/s-2006-957452

Reference yield:

(S)-Mosher acid (17257-71-5,20445-31-2,56135-03-6,81655-41-6) + Acetic acid (1R,7R,12R)-7,12-dihydroxy-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-1-(6-methyl-3-oxo-2-phenyl-2,3-dihydro-pyridazin-4-ylmethyl)-dodecyl ester (209053-03-2) → C73H91F9N2O13

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 6h; Ambient temperature;

DOI:10.1055/s-2006-957452

upstream raw materials:

phenylhydrazine

Acetic acid (1R,7R,12R)-7,12-dihydroxy-1-(5-hydroxy-5-methyl-2-oxo-2,5-dihydro-furan-3-ylmethyl)-12-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-dodecyl ester

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