Technology Process of 1-<1-(3,4-dimethoxyphenyl)-3-phenyl-2-propyl>-4-methylpiperazine
There total 6 articles about 1-<1-(3,4-dimethoxyphenyl)-3-phenyl-2-propyl>-4-methylpiperazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium iodide;
In
N,N-dimethyl-formamide;
at 125 - 130 ℃;
for 5h;
DOI:10.1135/cccc19841002
- Guidance literature:
-
Multi-step reaction with 6 steps
1: NaOEt / ethanol / 1)reflux 3.5h 2)stand overnight
2: HCl / acetic acid; H2O / 1)35 - 50 deg C 2)room temp., 48h
3: 80 percent / 10percentHCl / 6 h / Heating
4: 100 percent / NaBH4 / ethanol / 5 h / Heating
5: 89 percent / SOCl2 / benzene / 1.5 h / Heating
6: 7.5 percent / KI / dimethylformamide / 5 h / 125 - 130 °C
With
hydrogenchloride; sodium tetrahydroborate; thionyl chloride; sodium ethanolate; potassium iodide;
In
ethanol; water; acetic acid; N,N-dimethyl-formamide; benzene;
DOI:10.1135/cccc19841002
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 100 percent / NaBH4 / ethanol / 5 h / Heating
2: 89 percent / SOCl2 / benzene / 1.5 h / Heating
3: 7.5 percent / KI / dimethylformamide / 5 h / 125 - 130 °C
With
sodium tetrahydroborate; thionyl chloride; potassium iodide;
In
ethanol; N,N-dimethyl-formamide; benzene;
DOI:10.1135/cccc19841002
