S(+)-Mianserin

Base Information

Chemical Name:S(+)-Mianserin
CAS No.:51152-88-6
Molecular Formula:C₁₈H₂₀N₂
Molecular Weight:264.37
Hs Code.:
Mol file:51152-88-6.mol

Synonyms:Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-, (S)-; (+)-(S)-Mianserin; (+)-Mianserin;(S)-Mianserin; Mianserin, (+)-; S(+)-Mianserin

Suppliers and Price of S(+)-Mianserin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(+)-Mianserin
25mg
$ 395.00

American Custom Chemicals Corporation
S(+)-MIANSERIN 95.00%
5MG
$ 502.46

Total 11 raw suppliers

Chemical Property of S(+)-Mianserin

Chemical Property:

Vapor Pressure:5.65E-07mmHg at 25°C
Boiling Point:411.3°Cat760mmHg
Flash Point:186.1°C
PSA：6.48000
Density:1.18g/cm³
LogP:3.08680

Purity/Quality:

99% ^*data from raw suppliers

(S)-(+)-Mianserin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (S)-(+)-Mianserin is serotonin receptor antagonist. Antidepressant.

Technology Process of S(+)-Mianserin

There total 12 articles about S(+)-Mianserin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 136315-25-8
(+)-Desmethylmianserin

: 74-88-4
methyl iodide

: 51152-88-6
(S)-(+)-mianserin

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 24 - 25 ℃; for 2.5h;
DOI:10.3762/bjoc.11.164

Reference yield:

: 24219-97-4
mianserin

: 51152-88-6
(S)-(+)-mianserin

: 78684-63-6
(-)-Mianserin

Guidance literature:: Title compound not separated from byproducts;

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 642442-08-8
(14bR)-2-[(1'S)-1'-phenylethyl]-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine

: 51152-88-6
(S)-(+)-mianserin

: 78684-63-6
(-)-Mianserin

Guidance literature:: (14bR)-2-[(1'S)-1'-phenylethyl]-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine; With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; water; for 3h; atmospheric pressure;

formaldehyd; In ethanol; water; at 10 ℃;

With sodium tetrahydroborate; In ethanol; water; Title compound not separated from byproducts;
DOI:10.1016/S0957-4166(03)00582-2