3-[[2-(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]benzamide

Base Information

Chemical Name:3-[[2-(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]benzamide
CAS No.:70853-29-1
Molecular Formula:C₂₁H₂₆ClN₃O₃
Molecular Weight:403.909
Hs Code.:
ChEMBL ID:CHEMBL10927
DSSTox Substance ID:DTXSID801151577

Synonyms:CHEMBL10927;SCHEMBL11374860;DTXSID801151577;3-[[2-(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]benzamide;70853-29-1

Suppliers and Price of 3-[[2-(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[[2-(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]benzamide

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:403.1662694
Heavy Atom Count:28
Complexity:480

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)CCNC(=O)C1=CC(=CC=C1)NC(=O)COC2=CC=C(C=C2)Cl

Technology Process of 3-[[2-(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]benzamide

There total 4 articles about 3-[[2-(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70853-28-0
3-[2-(4-chloro-phenoxy)-acetylamino]-benzoic acid

: 100-36-7
N,N-diethylethylenediamine

: 70853-29-1
3-(p-Chlorphenoxyacetamido)-N-(2-diethylaminoethyl)-benzamid

Guidance literature:: With chloroformic acid ethyl ester; triethylamine; In dichloromethane; for 1h; Yield given;
DOI:10.1021/jm00361a022

Reference yield:

: 99-05-8,159139-79-4
meta-aminobenzoic acid

: 70853-29-1
3-(p-Chlorphenoxyacetamido)-N-(2-diethylaminoethyl)-benzamid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CHCl₃ / 5 h / Heating

2: triethylamine, ethyl chloroformate / CH₂Cl₂ / 1 h

With chloroformic acid ethyl ester; triethylamine; In dichloromethane; chloroform;
DOI:10.1021/jm00361a022

Reference yield:

: 4122-68-3
4-chlorophenyloxyacetyl chloride

: 70853-29-1
3-(p-Chlorphenoxyacetamido)-N-(2-diethylaminoethyl)-benzamid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CHCl₃ / 5 h / Heating

2: triethylamine, ethyl chloroformate / CH₂Cl₂ / 1 h

With chloroformic acid ethyl ester; triethylamine; In dichloromethane; chloroform;
DOI:10.1021/jm00361a022