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2-hydroxy-3-[(1S,3R)-3-(4-{[4-(trifluoromethyl)benzyl]oxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4H-chromen-4-one

Base Information Edit
  • Chemical Name:2-hydroxy-3-[(1S,3R)-3-(4-{[4-(trifluoromethyl)benzyl]oxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4H-chromen-4-one
  • CAS No.:104563-61-3
  • Molecular Formula:C33H25F3O4
  • Molecular Weight:542.554
  • Hs Code.:
  • Mol file:104563-61-3.mol
2-hydroxy-3-[(1S,3R)-3-(4-{[4-(trifluoromethyl)benzyl]oxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4H-chromen-4-one

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Suppliers and Price of 2-hydroxy-3-[(1S,3R)-3-(4-{[4-(trifluoromethyl)benzyl]oxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4H-chromen-4-one
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Business phase:
The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of 2-hydroxy-3-[(1S,3R)-3-(4-{[4-(trifluoromethyl)benzyl]oxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4H-chromen-4-one Edit
Chemical Property:
  • Vapor Pressure:2.87E-17mmHg at 25°C 
  • Boiling Point:640.2°Cat760mmHg 
  • Flash Point:341°C 
  • Density:1.348g/cm3 
Purity/Quality:

99% *data from raw suppliers

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Technology Process of 2-hydroxy-3-[(1S,3R)-3-(4-{[4-(trifluoromethyl)benzyl]oxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4H-chromen-4-one

There total 15 articles about 2-hydroxy-3-[(1S,3R)-3-(4-{[4-(trifluoromethyl)benzyl]oxy}phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 5 steps
1.1: sulfuric acid / water / 8 h / Reflux
1.2: polyphosphoric acid / 1 h / 80 °C
2.1: hydrogen bromide / acetic acid / 6 h / Reflux
3.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C
4.1: sodium tetrahydroborate / ethanol / 2 h / 20 °C
5.1: toluene-4-sulfonic acid / dichloromethane / 6 h / Reflux
With sodium tetrahydroborate; sulfuric acid; hydrogen bromide; sodium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; ethanol; dichloromethane; water; acetic acid;
DOI:10.1007/s12039-010-0071-2
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