103772-30-1

Basic information

• Product Name: 3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]tetralin-1-ol
• Synonyms: 3-(4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-1,2,3,4-tetrahydronaphthalen-1-ol
• CAS NO: 103772-30-1
• Molecular Formula: C₂₄H₂₁F₃O₂
• Molecular Weight: 398.42
• Mol File: 103772-30-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 508.8°C at 760 mmHg
• Flash Point: 220.2°C
• Density: 1.262g/cm³
• Vapor Pressure: 3.55E-11mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: 3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]tetralin-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]tetralin-1-ol(103772-30-1)
• EPA Substance Registry System: 3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]tetralin-1-ol(103772-30-1)

Safety Data

• Hazardous Substances Data: 103772-30-1(Hazardous Substances Data)

Upstream product

• 118806-75-0 3-p-methoxyphenyl-2-carboxy-4-phenylbutyric acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 7443-25-6 dimethyl 2-(4-methoxybenzylidene)malonate 
• 1333110-92-1 C₂₀H₂₂O₅ 
• 171818-87-4 3-hydroxy-3-(4-methoxy-phenyl)-4-phenyl-butyric acid ethyl ester 
• 171818-88-5 ethyl 3-(4-methoxyphenyl)-4-phenylbutanoate 
• 90035-32-8 3-(4-hydroxyphenyl)-3,4-dihydronaphthalen-1(2H)-one 
• 103-80-0 phenylacetyl chloride 
• 100-66-3 methoxybenzene 
• 118806-78-3 3-(4-methoxyphenyl)-4-phenylbutanoic acid 
• 61696-79-5 3,4-dihydro-3-(4-methoxyphenyl)naphthalene-1(2H)-one 
• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 287974-84-9 3-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-3,4-dihydro-2H-naphthalen-1-one 

Downstream Products

• 807609-63-8 1-bromo-3-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-1,2,3,4-tetrahydro-naphthalene 
• 104563-61-3 cis-4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin 
• 104563-61-3 trans-4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin 

Relevant articles and documents

Simple synthesis and biological evaluation of flocoumafen and its structural isomers

Simple synthesis and biological properties of flocoumafen 1 and its structural isomers are described. The key synthetic strategies involve Knoevenagel condensation, Grignard reaction, intramolecular ring cyclization and coupling reaction. Flocoumafen 1 was easily separated into cis and trans forms using flash column chromatography. They were then evaluated for suppression of LPS-induced NO generation and anti-excitotoxicity in vitro. It was found that the trans-flocoumafen was potent suppressor of NO generation with the concentration of 10 μM in vitro, while no significant effect for neurotoxicity in cultured cortical neurons. Indian Academy of Sciences.