118806-75-0

Basic information

• Product Name: 3-p-methoxyphenyl-2-carboxy-4-phenylbutyric acid
• CAS NO: 118806-75-0
• Molecular Weight: 314.338
• Mol File: 118806-75-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-p-methoxyphenyl-2-carboxy-4-phenylbutyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-p-methoxyphenyl-2-carboxy-4-phenylbutyric acid(118806-75-0)
• EPA Substance Registry System: 3-p-methoxyphenyl-2-carboxy-4-phenylbutyric acid(118806-75-0)

Safety Data

• Hazardous Substances Data: 118806-75-0(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 7443-25-6 dimethyl 2-(4-methoxybenzylidene)malonate 
• 1333110-92-1 C₂₀H₂₂O₅ 
• 6768-23-6 diethyl-2-(4-methoxybenzylidene)malonate 

Downstream Products

• 104563-61-3 cis-4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin 
• 104563-61-3 trans-4-hydroxy-3-[1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin 
• 90035-32-8 3-(4-hydroxyphenyl)-3,4-dihydronaphthalen-1(2H)-one 
• 103772-30-1 1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]naphthalen-1-ol 
• 287974-84-9 3-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-3,4-dihydro-2H-naphthalen-1-one 
• 61696-79-5 3,4-dihydro-3-(4-methoxyphenyl)naphthalene-1(2H)-one 
• 118806-78-3 3-(4-methoxyphenyl)-4-phenylbutanoic acid 

Relevant articles and documents

Simple synthesis and biological evaluation of flocoumafen and its structural isomers

Simple synthesis and biological properties of flocoumafen 1 and its structural isomers are described. The key synthetic strategies involve Knoevenagel condensation, Grignard reaction, intramolecular ring cyclization and coupling reaction. Flocoumafen 1 was easily separated into cis and trans forms using flash column chromatography. They were then evaluated for suppression of LPS-induced NO generation and anti-excitotoxicity in vitro. It was found that the trans-flocoumafen was potent suppressor of NO generation with the concentration of 10 μM in vitro, while no significant effect for neurotoxicity in cultured cortical neurons. Indian Academy of Sciences.