Boc-Aminooxy-PEG2-Azide

Base Information

Chemical Name:Boc-Aminooxy-PEG2-Azide
CAS No.:252378-68-0
Molecular Formula:C₁₁H₂₂N₄O₅
Molecular Weight:290.319
Hs Code.:
Mol file:252378-68-0.mol

Synonyms:

Suppliers and Price of Boc-Aminooxy-PEG2-Azide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
t-Boc-Aminooxy-PEG2-azide 98%
1 G
$ 1400.00

BroadPharm
t-Boc-Aminooxy-PEG2-azide 98%
250 MG
$ 480.00

Total 5 raw suppliers

Chemical Property of Boc-Aminooxy-PEG2-Azide

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

t-Boc-Aminooxy-PEG2-azide 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description t-Boc-Aminooxy-PEG2-azide is a click chemistry crosslinker molecule. The azide group enables PEGylation via Click Chemistry. The protected aminooxy can be deprotected under acidic conditions and then can react with an aldehyde or ketone group to form a stable oxime linkage.

Technology Process of Boc-Aminooxy-PEG2-Azide

There total 3 articles about Boc-Aminooxy-PEG2-Azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 36016-38-3
tert-Butyl N-hydroxycarbamate

: 530151-56-5
1-(2-azidoethoxy)-2-(2-bromoethoxy)ethane

: 252378-68-0
C₁₁H₂₂N₄O₅

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 60 ℃; for 13h; Inert atmosphere;

Reference yield:

: 86520-52-7
2-[2-(2-azidoethoxy)ethoxy]ethanol

: 252378-68-0
C₁₁H₂₂N₄O₅

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; carbon tetrabromide / dichloromethane / 13 h / 0 - 20 °C / Inert atmosphere

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 13 h / 60 °C / Inert atmosphere

With carbon tetrabromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In dichloromethane; acetonitrile;

Reference yield:

: 5197-62-6
2-[2-(chloroethoxy)ethoxy]ethanol

: 252378-68-0
C₁₁H₂₂N₄O₅

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide / N,N-dimethyl-formamide / 13 h / 100 °C / Inert atmosphere

2: triphenylphosphine; carbon tetrabromide / dichloromethane / 13 h / 0 - 20 °C / Inert atmosphere

3: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 13 h / 60 °C / Inert atmosphere

With sodium azide; carbon tetrabromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;