Isobonducellin

Base Information

• Chemical Name: Isobonducellin
• CAS No.: 610778-85-3
• Molecular Formula: C₁₇H₁₄O₄
• Molecular Weight: 282.296
• Mol file: 610778-85-3.mol

Synonyms:

Chemical Property of Isobonducellin

Chemical Property:

• Melting Point: 156-158 °C
• Boiling Point: 526.3±50.0 °C(Predicted)
• PKA: 7.58±0.20(Predicted)
• Density: 1.318±0.06 g/cm3(Predicted)

Purity/Quality:

98%Min ^*data from raw suppliers

Isobonducellin 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Isobonducellin

There total 7 articles about Isobonducellin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

7-hydroxy-2,3-dihydro-4H-chromen-4-one (76240-27-2) + 4-methoxy-benzaldehyde (123-11-5) → (Z)-7-hydroxy-3-(4'-methoxybenzylidene)chroman-4-one (610778-85-3)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 2h; Heating;

Reference yield: 42.0%

Bonducellin (83162-84-9,108634-42-0) → (Z)-7-hydroxy-3-(4'-methoxybenzylidene)chroman-4-one (610778-85-3)

Guidance literature:

In benzene; for 4h; Irradiation;

DOI:10.1016/j.bmc.2005.11.031

Reference yield:

7-hydroxy-2,3-dihydro-4H-chromen-4-one (76240-27-2) → (Z)-7-hydroxy-3-(4'-methoxybenzylidene)chroman-4-one (610778-85-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / perchloric acid; silica gel / 0.5 h / 90 - 100 °C

2: 42 percent / benzene / 4 h / Irradiation

With perchloric acid; silica gel; In benzene;

DOI:10.1016/j.bmc.2005.11.031

upstream raw materials:

7-hydroxy-2,3-dihydro-4H-chromen-4-one

4-methoxy-benzaldehyde

Bonducellin

O-methylresorcine

Downstream raw materials:

7-acetoxy-2,3-dihydro-3-(4-methoxybenzylidene)-1-benzopyran-4-one