N-tert-Butyl-α,α-divinylphenylacetamid

Base Information

• Chemical Name: N-tert-Butyl-α,α-divinylphenylacetamid
• CAS No.: 70179-02-1
• Molecular Formula: C₁₆H₂₁NO
• Molecular Weight: 243.349
• Mol file: 70179-02-1.mol

Synonyms:

Chemical Property of N-tert-Butyl-α,α-divinylphenylacetamid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-tert-Butyl-α,α-divinylphenylacetamid

There total 4 articles about N-tert-Butyl-α,α-divinylphenylacetamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α,α-bis(2-hydroxyethyl)phenylacetonitrile (10469-27-9) → N-tert-Butyl-α,α-divinylphenylacetamid (70179-02-1)

Guidance literature:

Multi-step reaction with 3 steps

1: Py

2: KOtBu / dimethylsulfoxide

3: H₂SO₄ / acetic acid

With pyridine; sulfuric acid; potassium tert-butylate; In acetic acid; dimethyl sulfoxide;

DOI:10.1021/jo01328a044

Reference yield:

2-phenyl-4-vinyloxy-2-(2-vinyloxy-ethyl)-butyronitrile (70179-05-4) → N-tert-Butyl-α,α-divinylphenylacetamid (70179-02-1)

Guidance literature:

Multi-step reaction with 4 steps

1: (hydrolysis)

2: Py

3: KOtBu / dimethylsulfoxide

4: H₂SO₄ / acetic acid

With pyridine; sulfuric acid; potassium tert-butylate; In acetic acid; dimethyl sulfoxide;

DOI:10.1021/jo01328a044

Reference yield:

α,α-Bis-(β-tosyloxyethyl)-phenylacetonitril (70179-04-3) → N-tert-Butyl-α,α-divinylphenylacetamid (70179-02-1)

Guidance literature:

Multi-step reaction with 2 steps

1: KOtBu / dimethylsulfoxide

2: H₂SO₄ / acetic acid

With sulfuric acid; potassium tert-butylate; In acetic acid; dimethyl sulfoxide;

DOI:10.1021/jo01328a044

upstream raw materials:

α,α-Divinylphenylacetonitril

tert-butyl alcohol

α,α-bis(2-hydroxyethyl)phenylacetonitrile

2-phenyl-4-vinyloxy-2-(2-vinyloxy-ethyl)-butyronitrile

Downstream raw materials:

α,α-Divinylphenylessigsaeure

β,β-Divinyl-β-phenylethanol

α,α-Divinylphenylacetamid