5-Methoxycarbonyl Deferasirox

Base Information

Chemical Name:5-Methoxycarbonyl Deferasirox
CAS No.:1395346-29-8
Molecular Formula:C₂₃H₁₇N₃O₆
Molecular Weight:431.404
Hs Code.:
Mol file:1395346-29-8.mol

Synonyms:

Suppliers and Price of 5-Methoxycarbonyl Deferasirox

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Methoxycarbonyl Deferasirox
2.5mg
$ 566.00

TRC
5-MethoxycarbonylDeferasirox
25mg
$ 1980.00

Medical Isotopes, Inc.
5-MethoxycarbonylDeferasirox
25 mg
$ 2800.00

American Custom Chemicals Corporation
5-METHOXYCARBONYL DEFERASIROX 95.00%
5MG
$ 502.89

Total 13 raw suppliers

Chemical Property of 5-Methoxycarbonyl Deferasirox

Chemical Property:

Boiling Point:732.7±70.0 °C(Predicted)
PKA:3.53±0.10(Predicted)
Density:1.43±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

5-Methoxycarbonyl Deferasirox ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 5-Methoxycarbonyl Deferasirox is an impurity of Deferasirox (D228650), orally active tridentate iron chelator.

Technology Process of 5-Methoxycarbonyl Deferasirox

There total 3 articles about 5-Methoxycarbonyl Deferasirox which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.28%

: 24798-47-8
2-(2-hydroxy-5-methoxycarbonylphenyl)-4H-1,3-benzoxazin-4-one

: 619-67-0
4-Hydrazinobenzoic acid

: 1395346-29-8
4-[5-(2-hydroxy-5-methoxycarbonylphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid

Guidance literature:: at 74 - 78 ℃; for 1.16667h;
DOI:10.1080/00397911.2011.580068

Reference yield:

: 636-46-4
4-hydroxyisophthalic acid

: 1395346-29-8
4-[5-(2-hydroxy-5-methoxycarbonylphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid

2: aluminum (III) chloride; dimethylsulfide

3: aluminum (III) chloride; pyridine; thionyl chloride / o-xylene / 1 h / 110 - 120 °C

4: 1.17 h / 74 - 78 °C

With pyridine; aluminum (III) chloride; thionyl chloride; dimethylsulfide; sulfuric acid; In o-xylene;
DOI:10.1080/00397911.2011.580068

Reference yield:

: 5985-24-0
dimethyl 4-hydroxyisophthalate

: 1395346-29-8
4-[5-(2-hydroxy-5-methoxycarbonylphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: aluminum (III) chloride; dimethylsulfide

2: aluminum (III) chloride; pyridine; thionyl chloride / o-xylene / 1 h / 110 - 120 °C

3: 1.17 h / 74 - 78 °C

With pyridine; aluminum (III) chloride; thionyl chloride; dimethylsulfide; In o-xylene;
DOI:10.1080/00397911.2011.580068