1-(3-fluorophenyl)Pyrrolidine

Base Information

Chemical Name:1-(3-fluorophenyl)Pyrrolidine
CAS No.:139909-17-4
Molecular Formula:C₁₀H₁₂FN
Molecular Weight:165.21
Hs Code.:
DSSTox Substance ID:DTXSID50567178
Nikkaji Number:J2.382.595C
Wikidata:Q82452978
Mol file:139909-17-4.mol

Synonyms:1-(3-fluorophenyl)Pyrrolidine;139909-17-4;1-(3-Fluorophenyl)-Pyrrolidine;Pyrrolidine, 1-(3-fluorophenyl)-;SCHEMBL255378;DTXSID50567178

Suppliers and Price of 1-(3-fluorophenyl)Pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 1-(3-fluorophenyl)Pyrrolidine

Chemical Property:

PSA：3.24000
LogP:2.49090
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:165.095377549
Heavy Atom Count:12
Complexity:143

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C2=CC(=CC=C2)F

Technology Process of 1-(3-fluorophenyl)Pyrrolidine

There total 3 articles about 1-(3-fluorophenyl)Pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 110-52-1
1,4-dibromo-butane

: 372-19-0
meta-fluoroaniline

: 139909-17-4
1-(3-fluorophenyl)pyrrolidine

Guidance literature:: With potassium carbonate; potassium iodide; In acetonitrile; at 90 ℃; for 12h;
DOI:10.1021/jacs.5b05086

Reference yield: 83.0%

: 123-75-1
pyrrolidine

: 625-98-9
3-chlorofluorobenzene

: 139909-17-4
1-(3-fluorophenyl)pyrrolidine

Guidance literature:: With C₄₀H₄₄ClN₃Pd; potassium tert-butylate; In toluene; at 110 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.tet.2018.07.052

Reference yield: 80.0%

: 123-75-1
pyrrolidine

: 372-18-9
1,3-Difluorobenzene

: 139909-17-4
1-(3-fluorophenyl)pyrrolidine

Guidance literature:: pyrrolidine; With lithium hexamethyldisilazane; In tetrahydrofuran; at 80 ℃; for 0.166667h; Sealed tube;

1,3-Difluorobenzene; In tetrahydrofuran; at 80 ℃; for 3h; Sealed tube;
DOI:10.1002/chem.201604098