D,L-aspartic acid methyl ester hydantoin

Base Information

• Chemical Name: D,L-aspartic acid methyl ester hydantoin
• CAS No.: 78212-20-1
• Molecular Formula: C₆H₈N₂O₄
• Molecular Weight: 172.141
• Mol file: 78212-20-1.mol

Synonyms:

Chemical Property of D,L-aspartic acid methyl ester hydantoin

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D,L-aspartic acid methyl ester hydantoin

There total 4 articles about D,L-aspartic acid methyl ester hydantoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

methanol (67-56-1) + 5-hydantoinacetic acid (5427-26-9) → D,L-aspartic acid methyl ester hydantoin (78212-20-1,63760-88-3)

Guidance literature:

With thionyl chloride; for 1h; Ambient temperature;

Reference yield:

L-Hydroorotsaeuremethylester (39681-15-7) + acetic acid (64-19-7,77671-22-8) → D,L-aspartic acid methyl ester hydantoin (78212-20-1,63760-88-3)

Guidance literature:

With sodium methylate; Yield given. Multistep reaction; 1.) methanol, reflux, 3 h;

DOI:10.1021/jo00374a044

Reference yield:

[(2,5-dioxo-imidazolidin-4-yl)-acetyl]-urea (198337-26-7) → D,L-aspartic acid methyl ester hydantoin (78212-20-1,63760-88-3)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH

With potassium hydroxide;

upstream raw materials:

methanol

5-hydantoinacetic acid

L-Hydroorotsaeuremethylester

acetic acid