4-Phenyl-2-(piperidin-1-yl)quinazoline

Base Information

Chemical Name:4-Phenyl-2-(piperidin-1-yl)quinazoline
CAS No.:14005-51-7
Molecular Formula:C19H19N3
Molecular Weight:289.38
Hs Code.:
DSSTox Substance ID:DTXSID10358069
Wikidata:Q82138348
ChEMBL ID:CHEMBL1599920
Mol file:14005-51-7.mol

Synonyms:4-phenyl-2-(piperidin-1-yl)quinazoline;14005-51-7;4-Phenyl-2-piperidin-1-yl-quinazoline;Quinazoline, 4-phenyl-2-(1-piperidinyl)-;4-phenyl-2-piperidin-1-ylquinazoline;SMR000120698;CBMicro_035015;Oprea1_300353;MLS000528124;SCHEMBL6335702;CHEMBL1599920;DTXSID10358069;HMS1689D11;HMS2162J08;HMS3313K18;STK862224;AKOS000638510;4-phenyl-2-(1-piperidinyl)quinazoline;CCG-105128;UPCMLD0ENAT5445958:001;BIM-0034930.P001;SR-01000414285;SR-01000414285-1;Z94798367;F0257-0071

Suppliers and Price of 4-Phenyl-2-(piperidin-1-yl)quinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Phenyl-2-(piperidin-1-yl)quinazoline

Chemical Property:

PSA：29.02000
LogP:4.35210
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:289.157897619
Heavy Atom Count:22
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=CC=CC=C4

Technology Process of 4-Phenyl-2-(piperidin-1-yl)quinazoline

There total 4 articles about 4-Phenyl-2-(piperidin-1-yl)quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1530-87-6
1-piperidinylcarbonnitrile

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 14005-51-7
4-phenyl-2-(piperidin-1-yl)quinazoline

Guidance literature:: With potassium tert-butylate; In N,N-dimethyl-formamide; at 110 ℃; for 12h;
DOI:10.1016/j.tetlet.2017.02.033

Reference yield: 58.0%

: 110-89-4
piperidine

: 4172-92-3
N-benzyl-N′-phenylcarbodiimide

: 14005-51-7
4-phenyl-2-(piperidin-1-yl)quinazoline

Guidance literature:: With oxygen; copper diacetate; In toluene; at 100 ℃; for 20h;
DOI:10.1002/adsc.201000469

Reference yield: 50.0%

: 13047-06-8
o-bromobenzophenone

: 17238-53-8,94052-13-8,100417-03-6
piperidinylguanidinium sulfate

: 14005-51-7
4-phenyl-2-(piperidin-1-yl)quinazoline

Guidance literature:: o-bromobenzophenone; piperidinylguanidinium sulfate; With caesium carbonate; L-proline; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere;

With copper(l) iodide; caesium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 40h; Inert atmosphere;
DOI:10.1055/s-0029-1216871