2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide

Base Information

Chemical Name:2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide
CAS No.:74537-77-2
Molecular Formula:C₈H₁₁N₃OS
Molecular Weight:197.261
Hs Code.:
DSSTox Substance ID:DTXSID101327779
ChEMBL ID:CHEMBL1526762
Mol file:74537-77-2.mol

Synonyms:2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamide;74537-77-2;2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide;2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide;BAS 03014660;MLS000693131;SCHEMBL2855549;CHEMBL1526762;DTXSID101327779;HMS1680B14;HMS2759H24;STK927344;AKOS000563133;SMR000284759;CS-0315618;F0176-0103

Suppliers and Price of 2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]ACETAMIDE 95.00%
5MG
$ 505.26

Total 1 raw suppliers

Chemical Property of 2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:197.06228316
Heavy Atom Count:13
Complexity:178

Purity/Quality:: 2-[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)SCC(=O)N)C

Technology Process of 2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide

There total 4 articles about 2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 22325-27-5,131321-42-1
4,6-dimethyl-2-meraptopyrimidine

: 79-07-2
Chloroacetamide

: 74537-77-2
2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamid

Guidance literature:: 4,6-dimethyl-2-meraptopyrimidine; With sodium carbonate; potassium iodide; In dimethyl sulfoxide; at 20 ℃; for 0.25h;

Chloroacetamide; In dimethyl sulfoxide; for 2h;
DOI:10.1021/acs.jmedchem.5b01517

Reference yield: 70.0%

: 62501-45-5
2-mercapto-4,6-dimethyl-pyrimidine hydrochloride

: 79-07-2
Chloroacetamide

: 74537-77-2
2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamid

Guidance literature:: With potassium hydroxide; In water; at 20 ℃; Cooling with ice;
DOI:10.2174/1570178617999200601165334

Reference yield:

: 123-54-6,81235-32-7
acetylacetone

: 74537-77-2
2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / ethanol / 48.5 h / 20 °C / Reflux

2.1: sodium carbonate; potassium iodide / dimethyl sulfoxide / 0.25 h / 20 °C

2.2: 2 h

With sulfuric acid; sodium carbonate; potassium iodide; In ethanol; dimethyl sulfoxide;
DOI:10.1021/acs.jmedchem.5b01517