2-Amino-2'-fluorobenzophenone

Base Information

Chemical Name:2-Amino-2'-fluorobenzophenone
CAS No.:1581-13-1
Molecular Formula:C13H10FNO
Molecular Weight:215.227
Hs Code.:2922399090
European Community (EC) Number:216-427-2
DSSTox Substance ID:DTXSID40166376
Nikkaji Number:J206.820F
Wikidata:Q83035566
Mol file:1581-13-1.mol

Synonyms:1581-13-1;(2-Aminophenyl)(2-fluorophenyl)methanone;2-Amino-2'-fluorobenzophenone;(2-aminophenyl)-(2-fluorophenyl)methanone;Methanone, (2-aminophenyl)(2-fluorophenyl)-;EINECS 216-427-2;2-(2-fluorobenzoyl)aniline;2-Amino-2 inverted exclamation mark -fluoro-benzophenone;Methanone,(2-aminophenyl)(2-fluorophenyl)-;SCHEMBL5282720;2-Amino-2/'-fluorobenzophenone;NRAJMXHXQHCBHO-UHFFFAOYSA-;DTXSID40166376;Benzophenone, 2-amino-2'-fluoro-;BCP10585;AKOS005259586;SB79465;(2-Aminophenyl)(2-fluorophenyl)methanone #;A3482;BB 0260882;FT-0646932;Y13600;J-507756

Suppliers and Price of 2-Amino-2'-fluorobenzophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-2''-fluorobenzophenone
1g
$ 1325.00

Matrix Scientific
(2-Aminophenyl)(2-fluorophenyl)methanone
2.500g
$ 700.00

Matrix Scientific
(2-Aminophenyl)(2-fluorophenyl)methanone
500mg
$ 300.00

Matrix Scientific
(2-Aminophenyl)(2-fluorophenyl)methanone
1g
$ 420.00

Crysdot
(2-Aminophenyl)(2-fluorophenyl)methanone 95+%
5g
$ 1126.00

Crysdot
(2-Aminophenyl)(2-fluorophenyl)methanone 95+%
1g
$ 419.00

Biosynth Carbosynth
2-Amino-2'-fluorobenzophenone
50 mg
$ 325.00

Biosynth Carbosynth
2-Amino-2'-fluorobenzophenone
25 mg
$ 200.00

Biosynth Carbosynth
2-Amino-2'-fluorobenzophenone
10 mg
$ 125.00

Biosynth Carbosynth
2-Amino-2'-fluorobenzophenone
250 mg
$ 800.00

Total 25 raw suppliers

Chemical Property of 2-Amino-2'-fluorobenzophenone

Chemical Property:

Melting Point:126-128℃
Boiling Point:401.9 °C at 760 mmHg
PKA:-0.78±0.10(Predicted)
Flash Point:196.8 °C
PSA：43.09000
Density:1.236 g/cm³
LogP:3.22010
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Slightly, Heated)
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:215.074642105
Heavy Atom Count:16
Complexity:256

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-2''-fluorobenzophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)C2=CC=CC=C2F)N
Uses 2-Amino-2''-fluorobenzophenone is an intermediate in the preparation of the anticholesteremic Pitavastatin.

Technology Process of 2-Amino-2'-fluorobenzophenone

There total 12 articles about 2-Amino-2'-fluorobenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: C₁₃H₈FNO

: 1581-13-1
2-amino-2'-fluorobenzophenone

Guidance literature:: With palladium 10% on activated carbon; hydrogen; triethylamine; In tetrahydrofuran; at 25 ℃; for 12h; under 7500.75 Torr; Autoclave;
DOI:10.1002/cctc.201600047

Reference yield: 81.0%

: C₁₃H₁₀FNO₄S

: 1581-13-1
2-amino-2'-fluorobenzophenone

Guidance literature:: With dipotassium hydrogenphosphate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; triphenylphosphine; In 1,4-dioxane; at 25 ℃; for 8h; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1002/chem.201903816

Reference yield: 57.0%

: 348-53-8
2-fluorophenyl lithium

: 133776-41-7
anthranilic acid N-methoxy-N-methylamide

: 1581-13-1
2-amino-2'-fluorobenzophenone

Guidance literature:: anthranilic acid N-methoxy-N-methylamide; With n-butyllithium; In tetrahydrofuran; hexane; at -100 ℃; Inert atmosphere;

2-fluorophenyl lithium; In tetrahydrofuran; hexane; at -100 ℃; Inert atmosphere;
DOI:10.1021/jm800506v