Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester

Base Information

• Chemical Name: Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester
• CAS No.: 64350-17-0
• Molecular Formula: C₆₂H₉₇Cl₃NO₈P
• Molecular Weight: 1121.79
• Mol file: 64350-17-0.mol

Synonyms:

Chemical Property of Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester

There total 4 articles about Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-α,β-distearin (51063-97-9) → Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester (64350-17-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 1-methyl-imidazole

2: isopentyl nitrite, Py

3: 2,4,6-triisopropylbenzenesulfonyl chloride, Py

With pyridine; 1-methyl-1H-imidazole; 2,4,6-triisopropylphenylsulfonyl chloride; isopentyl nitrite;

Reference yield:

bromo-triphenyl-methane (596-43-0) → Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester (64350-17-0)

Guidance literature:

Multi-step reaction with 2 steps

2: 2,4,6-triisopropylbenzenesulfonyl chloride, Py

With pyridine; 2,4,6-triisopropylphenylsulfonyl chloride;

Reference yield:

Octadecanoic acid 1-octadecanoyloxymethyl-2-[phenylamino-(2,2,2-trichloro-ethoxy)-phosphoryloxy]-ethyl ester (64350-15-8) → Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester (64350-17-0)

Guidance literature:

Multi-step reaction with 2 steps

1: isopentyl nitrite, Py

2: 2,4,6-triisopropylbenzenesulfonyl chloride, Py

With pyridine; 2,4,6-triisopropylphenylsulfonyl chloride; isopentyl nitrite;

upstream raw materials:

N-tritylethanolamine

Octadecanoic acid 2-[hydroxy-(2,2,2-trichloro-ethoxy)-phosphoryloxy]-1-octadecanoyloxymethyl-ethyl ester

DL-α,β-distearin

bromo-triphenyl-methane

Downstream raw materials:

N-Trityl O-(1,2-disteaoryl-sn-glycero-3-phosphoryl)-ethanolamin

distearylphosphatidylethanolamine