2-(Tritylamino)ethanol

Base Information

• Chemical Name: 2-(Tritylamino)ethanol
• CAS No.: 24070-16-4
• Molecular Formula: C21H21NO
• Molecular Weight: 303.404
• DSSTox Substance ID: DTXSID70389551
• Nikkaji Number: J1.691.398G
• Wikidata: Q82185441
• Mol file: 24070-16-4.mol

Synonyms:2-(tritylamino)ethanol;24070-16-4;2-(Trityl-amino)-ethanol;N-tritylethanolamine;Ethanol, 2-[(triphenylmethyl)amino]-;Ethanol, 2-(tritylamino)- (8CI);2-(Triphenylmethylamino)ethanol;2-Tritylaminoethanol;N-(Triphenylmethyl)ethanolamine;N-Trityl-2-aminoethanol;N-trityl-2-aminoethanol;2-(N-tritylamino)ethanol;-2(Trityl-Amino)-Ethanol;SCHEMBL147990;N-(triphenylmethyl)ethanolamine;2-(triphenylmethylamino)ethanol;DTXSID70389551;GHSBJDZSBNDAGL-UHFFFAOYSA-N;CS-M3582;ZAA07016;MFCD00399829;AKOS000520327;AC-33893;AM804994;AS-39441;SR-01000317550;SR-01000317550-1

Chemical Property of 2-(Tritylamino)ethanol

Chemical Property:

• PSA: 32.26000
• LogP: 3.95130
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 303.162314293
• Heavy Atom Count: 23
• Complexity: 279

Purity/Quality:

99% ^*data from raw suppliers

2-(Trityl-amino)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCCO

Technology Process of 2-(Tritylamino)ethanol

There total 7 articles about 2-(Tritylamino)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trityl chloride (76-83-5) + ethanolamine (141-43-5) → N-tritylethanolamine (24070-16-4)

Guidance literature:

With potassium carbonate; In dichloromethane; at 0 - 20 ℃; for 3h;

DOI:10.1016/j.bmc.2019.01.006

Reference yield: 72.0%

trityl chloride (76-83-5) + ethanolamine (141-43-5) → N-tritylethanolamine (24070-16-4) + N,O-bistritylethanolamine (30035-57-5)

Guidance literature:

With 1,3-bis(3,4-diethylpyrrol-2-yl)-1,3-propanedione BF₂ complex; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1021/acs.orglett.8b00855

Reference yield:

2-amino-ethanol hydrochloride (2002-24-6) + trityl chloride (76-83-5) + triethylamine (121-44-8) + acetonitrile (75-05-8,26809-02-9) → N-tritylethanolamine (24070-16-4)

Guidance literature:

In dichloromethane;

upstream raw materials:

bromo-triphenyl-methane

ethanolamine

trityl chloride

2-amino-ethanol hydrochloride

Downstream raw materials:

N-Trityl-O-(1,2-dioctadecanoyl-sn-glycero-3-phosphoryl)-ethanolamin

N-Trityl O-(1,2-disteaoryl-sn-glycero-3-phosphoryl)-ethanolamin

Octadecanoic acid 1-octadecanoyloxymethyl-2-{(2,2,2-trichloro-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester

(Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-{(2,2,2-tribromo-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester