6-(Pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine

Base Information

Chemical Name:6-(Pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine
CAS No.:881291-07-2
Molecular Formula:C₁₁H₁₃N₃O₂S₂
Molecular Weight:283.375
Hs Code.:
European Community (EC) Number:844-007-4
Nikkaji Number:J3.530.266B
ChEMBL ID:CHEMBL4913167
Mol file:881291-07-2.mol

Synonyms:6-(pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine;881291-07-2;6-(pyrrolidin-1-ylsulfonyl)-1,3-benzothiazol-2-amine;6-pyrrolidin-1-ylsulfonyl-1,3-benzothiazol-2-amine;CHEMBL4913167;SCHEMBL17241705;STK850161;AKOS000268376;CS-0247252;EN300-36153;J3.530.266B;AB00674321-01;N,N-Tetramethylene-2-aminobenzothiazole-6-sulfonamide;F1420-1725;Z362763672

Suppliers and Price of 6-(Pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-(PYRROLIDIN-1-YLSULFONYL)-1,3-BENZOTHIAZOL-2-AMINE 95.00%
5G
$ 1590.46

American Custom Chemicals Corporation
6-(PYRROLIDIN-1-YLSULFONYL)-1,3-BENZOTHIAZOL-2-AMINE 95.00%
2.5G
$ 1255.54

American Custom Chemicals Corporation
6-(PYRROLIDIN-1-YLSULFONYL)-1,3-BENZOTHIAZOL-2-AMINE 95.00%
1G
$ 867.10

AK Scientific
6-(Pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine
100mg
$ 210.00

Total 3 raw suppliers

Chemical Property of 6-(Pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:283.04491901
Heavy Atom Count:18
Complexity:403

Purity/Quality:

97% ^*data from raw suppliers

6-(PYRROLIDIN-1-YLSULFONYL)-1,3-BENZOTHIAZOL-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(C1)S(=O)(=O)C2=CC3=C(C=C2)N=C(S3)N

Technology Process of 6-(Pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine

There total 4 articles about 6-(Pyrrolidine-1-sulfonyl)-1,3-benzothiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 88327-91-7
4-(pyrrolidin-1-ylsulfonyl)aniline

: 333-20-0
potassium thioacyanate

: 881291-07-2
6-(pyrrolidin-1-ylsulfonyl)benzo[d]thiazol-2-amine

Guidance literature:: With copper(II) sulfate; In methanol; for 3h; Reflux;
DOI:10.1021/acscombsci.5b00155

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 881291-07-2
6-(pyrrolidin-1-ylsulfonyl)benzo[d]thiazol-2-amine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 3 h / 0 - 20 °C

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 18 h

3: copper(II) sulfate / methanol / 3 h / Reflux

With palladium 10% on activated carbon; hydrogen; copper(II) sulfate; triethylamine; In methanol; dichloromethane; ethyl acetate;
DOI:10.1021/acscombsci.5b00155

Reference yield:

: 175278-37-2
1-((4-nitrophenyl)sulfonyl)pyrrolidine

: 881291-07-2
6-(pyrrolidin-1-ylsulfonyl)benzo[d]thiazol-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 18 h

2: copper(II) sulfate / methanol / 3 h / Reflux

With palladium 10% on activated carbon; hydrogen; copper(II) sulfate; In methanol; ethyl acetate;
DOI:10.1021/acscombsci.5b00155