7-Methoxy-2,2-dimethylchromane-6-carbaldehyde

Base Information

Chemical Name:7-Methoxy-2,2-dimethylchromane-6-carbaldehyde
CAS No.:97024-29-8
Molecular Formula:C₁₃H₁₆O₃
Molecular Weight:220.268
Hs Code.:
DSSTox Substance ID:DTXSID301161204
Mol file:97024-29-8.mol

Synonyms:7-methoxy-2,2-dimethylchromane-6-carbaldehyde;97024-29-8;7-methoxy-2,2-dimethyl-3,4-dihydrochromene-6-carbaldehyde;DTXSID301161204;AP-383/40724393;3,4-Dihydro-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-carboxaldehyde

Suppliers and Price of 7-Methoxy-2,2-dimethylchromane-6-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 7-Methoxy-2,2-dimethylchromane-6-carbaldehyde

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:220.109944368
Heavy Atom Count:16
Complexity:262

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(CCC2=CC(=C(C=C2O1)OC)C=O)C

Technology Process of 7-Methoxy-2,2-dimethylchromane-6-carbaldehyde

There total 7 articles about 7-Methoxy-2,2-dimethylchromane-6-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 32268-32-9
7-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehyde

: 74-88-4
methyl iodide

: 97024-29-8
7-methoxy-2,2-dimethylchroman-6-carbaldehyde

Guidance literature:: With potassium carbonate; at 20 ℃;
DOI:10.1039/d1nj01985f

Reference yield: 70.0%

: 20052-58-8
7-methoxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 97024-29-8
7-methoxy-2,2-dimethylchroman-6-carbaldehyde

Guidance literature:: With trichlorophosphate; In acetonitrile; at 20 - 60 ℃; for 13.5h; regioselective reaction;
DOI:10.1039/d0nj02125c

Reference yield:

: 31005-72-8
2,2-dimethylchroman-7-ol

: 97024-29-8
7-methoxy-2,2-dimethylchroman-6-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: acetone / 12 h / 56 °C

2: trichlorophosphate / acetonitrile / 13.5 h / 20 - 60 °C

With trichlorophosphate; In acetone; acetonitrile; 2: |Vilsmeier-Haack Formylation;
DOI:10.1039/d0nj02125c