2-(2-furylmethylsulfanyl)pyridine

Base Information

• Chemical Name: 2-(2-furylmethylsulfanyl)pyridine
• CAS No.: 856591-70-3
• Molecular Formula: C₁₀H₉NOS
• Molecular Weight: 191.254
• Mol file: 856591-70-3.mol

Synonyms:

Chemical Property of 2-(2-furylmethylsulfanyl)pyridine

Chemical Property:

• Vapor Pressure: 0.000931mmHg at 25°C
• Boiling Point: 313.1±27.0 °C(Predicted)
• PKA: 2.89±0.19(Predicted)
• Density: 1.22±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-((Furan-2-ylmethyl)thio)pyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-furylmethylsulfanyl)pyridine

There total 1 articles about 2-(2-furylmethylsulfanyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloropyridine (109-09-1) + 2-thiolomethyl-furan (98-02-2,175236-33-6) → C10H9NOS (856591-70-3)

Guidance literature:

2-thiolomethyl-furan; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 0.333333h;

2-chloropyridine; In tetrahydrofuran; at 40 ℃; for 16h;

DOI:10.1002/anie.201602264

Reference yield:

C10H9NOS (856591-70-3) → 2-(furan-2-ylmethyl)pyridine (106584-05-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.33 h / 20 °C

2: methylmagnesium bromide / tetrahydrofuran / 1 h / 20 °C

With methylmagnesium bromide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1002/anie.201602264

upstream raw materials:

2-chloropyridine

2-thiolomethyl-furan

Downstream raw materials:

2-(furan-2-ylmethyl)pyridine

Refernces