(1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-ylmethanol

Base Information

• Chemical Name: (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-ylmethanol
• CAS No.: 1398833-81-2
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.144
• Mol file: 1398833-81-2.mol

Synonyms:

Chemical Property of (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-ylmethanol

Chemical Property:

• Boiling Point: 245.5±8.0 °C(Predicted)
• Density: 1.175±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

3-Oxabicyclo[3.1.0]hexan-6-ylmethanol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-ylmethanol

There total 5 articles about (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.31%

ethyl (exo)-3-oxabicyclo[3.1.0]hexane-6-carboxylate (335599-07-0) → (3-oxa-bicyclo[3.1.0]hexan-6-yl)methanol (1398833-81-2)

Guidance literature:

3-Oxabicyclo<3.1.0>hexan-exo-6-carbonsaeure-ethylester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 1.5h;

With sodium sulfate; In tetrahydrofuran; for 1h;

Reference yield:

tert-butyl (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-carboxylate (1307304-62-6) → (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-ylmethanol (135577-15-0,1398833-81-2)

Guidance literature:

tert-butyl (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at -10 - 20 ℃; for 3h;

With water; rochelle salt; In tetrahydrofuran; diethyl ether; at -5 - 20 ℃; for 0.5h;

Reference yield:

(1R,5S,6R)-ethyl 3-oxabicyclo[3.1.0]hexane-6-carboxylate (81056-11-3) → (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-ylmethanol (135577-15-0,1398833-81-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

upstream raw materials:

ethyl (exo)-3-oxabicyclo[3.1.0]hexane-6-carboxylate

2,5-dihydrofuran

diazoacetic acid ethyl ester

tert-butyl (1R,5S,6R)-3-oxabicyclo[3.1.0]hexane-6-carboxylate