C₂₁H₂₅ClN₂O₄Si

Base Information

Chemical Name:C₂₁H₂₅ClN₂O₄Si
CAS No.:1415564-64-5
Molecular Formula:C₂₁H₂₅ClN₂O₄Si
Molecular Weight:432.979
Hs Code.:
Mol file:1415564-64-5.mol

C<sub>21</sub>H<sub>25</sub>ClN<sub>2</sub>O<sub>4</sub>Si

Synonyms:

Suppliers and Price of C₂₁H₂₅ClN₂O₄Si

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
3-(6-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-4-methylbenzoicacid
1g
$ 1540.00

Chemenu
3-(6-Chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-4-methylbenzoicacid 95%+
1g
$ 3003.00

Chemenu
3-(6-Chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-4-methylbenzoicacid 95%+
250mg
$ 1201.00

Chemenu
3-(6-Chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-4-methylbenzoicacid 95%+
100mg
$ 781.00

Total 3 raw suppliers

Chemical Property of C₂₁H₂₅ClN₂O₄Si

Chemical Property:

Purity/Quality:

>98% ^*data from raw suppliers

3-(6-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-4-methylbenzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of C₂₁H₂₅ClN₂O₄Si

There total 1 articles about C₂₁H₂₅ClN₂O₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 869335-22-8
6-chloro-4-nitro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine

: 586-30-1
3-hydroxy-4-methylbenzoic acid

: 1415564-64-5
C₂₁H₂₅ClN₂O₄Si

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 100 ℃; for 5h;
DOI:10.1021/jm500480k

Reference yield:

: 1415564-64-5
C₂₁H₂₅ClN₂O₄Si

: N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)-phenyl)-4-methyl-3-((1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / methanol

2: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 20 °C

With dmap; palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In methanol; dichloromethane;
DOI:10.1021/jm500480k

Reference yield:

: 1415564-64-5
C₂₁H₂₅ClN₂O₄Si

: 1315355-93-1
3-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: palladium 10% on activated carbon; hydrogen / methanol

2.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 20 °C

3.1: trifluoroacetic acid / dichloromethane / 5.5 h / 0 - 20 °C

3.2: 24 h / Alkaline conditions

With dmap; palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In methanol; dichloromethane;
DOI:10.1021/jm500480k