tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

Base Information

Chemical Name:tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate
CAS No.:2100306-71-4
Molecular Formula:C₁₂H₂₃BrO₅
Molecular Weight:327.216
Hs Code.:

Synonyms:

Suppliers and Price of tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
Bromo-PEG3-CH2CO2tBu 98%
250 MG
$ 650.00

Activate Scientific
Br-PEG3-CH2COOtBu 95+%
5 g
$ 1613.00

Activate Scientific
Br-PEG3-CH2COOtBu 95+%
1 g
$ 745.00

Activate Scientific
Br-PEG3-CH2COOtBu 95+%
250 mg
$ 350.00

Acrotein
Br-PEG3-CH2COOtBu 97%
0.5g
$ 302.50

Acrotein
Br-PEG3-CH2COOtBu 97%
0.25g
$ 201.66

Total 6 raw suppliers

Chemical Property of tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

Chemical Property:

Boiling Point:360.9±27.0 °C(Predicted)
Density:1.246±0.06 g/cm3(Predicted)

Purity/Quality:

99.3% ^*data from raw suppliers

Bromo-PEG3-CH2CO2tBu 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Bromo-PEG3-CH2CO2tBu is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Technology Process of tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

There total 2 articles about tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.7%

: 5414-19-7
1,1'-oxybis(2-bromo-ethane)

: 287174-32-7
(2-hydroxyethoxy)acetic acid tert-butyl ester

: 2100306-71-4
tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

Guidance literature:: (2-hydroxyethoxy)acetic acid tert-butyl ester; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.666667h; Inert atmosphere; Cooling with ice;

1,1'-oxybis(2-bromo-ethane); In N,N-dimethyl-formamide; for 4h; Inert atmosphere;

Reference yield:

: 5292-43-3
bromoacetic acid tert-butyl ester

: 2100306-71-4
tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere; Cooling with ice

2.1: sodium hydride / N,N-dimethyl-formamide / 0.67 h / 20 °C / Inert atmosphere; Cooling with ice

2.2: 4 h / Inert atmosphere

With sodium hydride; In N,N-dimethyl-formamide;