2-(1-Methoxycyclobutyl)ethan-1-ol

Base Information

• Chemical Name: 2-(1-Methoxycyclobutyl)ethan-1-ol
• CAS No.: 83237-26-7
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.187
• European Community (EC) Number: 969-932-1
• Mol file: 83237-26-7.mol

Synonyms:2-(1-methoxycyclobutyl)ethan-1-ol;83237-26-7;2-(1-Methoxycyclobutyl)ethanol;SCHEMBL23781888;AB93294;CID 12956085;EN300-213960

Chemical Property of 2-(1-Methoxycyclobutyl)ethan-1-ol

Chemical Property:

• Boiling Point: 82-84 °C(Press: 2 Torr)
• Density: 0.9984 g/cm3
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 130.099379685
• Heavy Atom Count: 9
• Complexity: 86.9

Purity/Quality:

97% ^*data from raw suppliers

2-(1-methoxycyclobutyl)ethan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1(CCC1)CCO

Technology Process of 2-(1-Methoxycyclobutyl)ethan-1-ol

There total 2 articles about 2-(1-Methoxycyclobutyl)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 5,7-dioxaspiro<3.5>nonane (73637-29-3) → Dimethoxymethane (109-87-5) + 1-hydroxy-1-(β-hydroxyethyl)cyclobutane (83237-27-8) + 1-methoxy-1-(β-hydroxyethyl)cyclobutane (83237-26-7)

Guidance literature:

With sulfuric acid; Yield given. Yields of byproduct given; to reflux, further reagent;

DOI:10.1007/BF00954189

Reference yield:

methylidenecyclobutane (1120-56-5) → 1-methoxy-1-(β-hydroxyethyl)cyclobutane (83237-26-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 49 percent / aq. H₂SO₄ / 1 h / 40 °C / further reagent

2: H₂SO₄ / to reflux

With sulfuric acid;

DOI:10.1007/BF00954189

upstream raw materials:

methanol

5,7-dioxaspiro<3.5>nonane

methylidenecyclobutane