(1E)-N-[2-(2-Bromo-4,5-dimethoxyphenyl)ethyl]-1-phenylethan-1-imine

Base Information

• Chemical Name: (1E)-N-[2-(2-Bromo-4,5-dimethoxyphenyl)ethyl]-1-phenylethan-1-imine
• CAS No.: 140616-37-1
• Molecular Formula: C18H20BrNO2
• Molecular Weight: 362.266
• DSSTox Substance ID: DTXSID00566318
• Mol file: 140616-37-1.mol

Synonyms:140616-37-1;DTXSID00566318;(1E)-N-[2-(2-Bromo-4,5-dimethoxyphenyl)ethyl]-1-phenylethan-1-imine

Chemical Property of (1E)-N-[2-(2-Bromo-4,5-dimethoxyphenyl)ethyl]-1-phenylethan-1-imine

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 361.06774
• Heavy Atom Count: 22
• Complexity: 355

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=NCCC1=CC(=C(C=C1Br)OC)OC)C2=CC=CC=C2

Technology Process of (1E)-N-[2-(2-Bromo-4,5-dimethoxyphenyl)ethyl]-1-phenylethan-1-imine

There total 1 articles about (1E)-N-[2-(2-Bromo-4,5-dimethoxyphenyl)ethyl]-1-phenylethan-1-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-bromo-4,5-dimethoxyphenylphenyl)ethan-1-amine (63375-81-5) + acetophenone (98-86-2) → [2-(2-Bromo-4,5-dimethoxy-phenyl)-ethyl]-[1-phenyl-eth-(E)-ylidene]-amine (140616-37-1)

Guidance literature:

In toluene; at 20 ℃; for 12h;

DOI:10.5555/ol007065r

Reference yield: 10.5%

[2-(2-Bromo-4,5-dimethoxy-phenyl)-ethyl]-[1-phenyl-eth-(E)-ylidene]-amine (140616-37-1) → 5,6-Dimethoxy-1-(1-phenyl-ethyl)-2,3-dihydro-1H-indole

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; for 2h;

DOI:10.3987/COM-93-S7

Reference yield:

[2-(2-Bromo-4,5-dimethoxy-phenyl)-ethyl]-[1-phenyl-eth-(E)-ylidene]-amine (140616-37-1) → 5,6-Dimethoxy-1-(1-phenyl-ethyl)-2,3-dihydro-1H-indole + N-2-(3,4-dimethoxyphenyl)ethyl-(1-phenylethylidene)amine (83100-97-4)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃;

DOI:10.5555/ol007065r

upstream raw materials:

2-(2-bromo-4,5-dimethoxyphenylphenyl)ethan-1-amine

acetophenone

Downstream raw materials:

N-2-(3,4-dimethoxyphenyl)ethyl-(1-phenylethylidene)amine