Quinolin-2-ylmethyl 4-methylbenzenesulfonate

Base Information

Chemical Name:Quinolin-2-ylmethyl 4-methylbenzenesulfonate
CAS No.:19820-77-0
Molecular Formula:C17H15 N O3 S
Molecular Weight:313.377
Hs Code.:2933499090
DSSTox Substance ID:DTXSID20427694
Mol file:19820-77-0.mol

Synonyms:quinolin-2-ylmethyl 4-methylbenzenesulfonate;19820-77-0;SCHEMBL6572241;DTXSID20427694;AKOS000118312;CS-0350868;EN300-14421;quinolin-2-ylmethyl 4-methylbenzene-1-sulfonate;(quinolin-2-yl)methyl 4-methylbenzene-1-sulfonate;(QUINOLIN-2-YL)METHYL 4-METHYLBENZENESULFONATE;Z104341278

Suppliers and Price of Quinolin-2-ylmethyl 4-methylbenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
QUINOLIN-2-YLMETHYL 4-METHYLBENZENESULFONATE 95.00%
5G
$ 1759.28

American Custom Chemicals Corporation
QUINOLIN-2-YLMETHYL 4-METHYLBENZENESULFONATE 95.00%
2.5G
$ 1363.65

American Custom Chemicals Corporation
QUINOLIN-2-YLMETHYL 4-METHYLBENZENESULFONATE 95.00%
1G
$ 925.31

Total 5 raw suppliers

Chemical Property of Quinolin-2-ylmethyl 4-methylbenzenesulfonate

Chemical Property:

Vapor Pressure:2.1E-09mmHg at 25°C
Boiling Point:493.6°C at 760 mmHg
Flash Point:252.3°C
PSA：64.64000
Density:1.295g/cm³
LogP:4.52950
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:313.07726451
Heavy Atom Count:22
Complexity:451

Purity/Quality:

99% ^*data from raw suppliers

QUINOLIN-2-YLMETHYL 4-METHYLBENZENESULFONATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCC2=NC3=CC=CC=C3C=C2

Technology Process of Quinolin-2-ylmethyl 4-methylbenzenesulfonate

There total 4 articles about Quinolin-2-ylmethyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1076-28-4
2-methylquinoline N-oxide

: 98-59-9
p-toluenesulfonyl chloride

: 19820-77-0
quinolin-2-ylmethyl 4-methylbenzenesulfonate

Guidance literature:: 2-methylquinoline N-oxide; With potassium carbonate; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere;

p-toluenesulfonyl chloride; In dichloromethane; at 0 - 20 ℃; for 4h; Reagent/catalyst; Solvent; Inert atmosphere;
DOI:10.1016/j.tetlet.2018.03.062

Reference yield: 69.0%

: 1076-28-4
2-methylquinoline N-oxide

: 98-59-9
p-toluenesulfonyl chloride

: 4377-41-7
2-Chloromethylquinoline

: 19820-77-0
quinolin-2-ylmethyl 4-methylbenzenesulfonate

: 1-methylimidazo[1,5-a]quinoline

Guidance literature:: With potassium carbonate; In acetonitrile; for 1h; from 0 deg C to room temp.;
DOI:10.1016/S0040-4039(96)02460-4

Reference yield:

: 91-63-4
2-methylquinoline

: 19820-77-0
quinolin-2-ylmethyl 4-methylbenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 22 h / 0 - 20 °C

2.1: potassium carbonate / dichloromethane / 0.25 h / 0 °C / Inert atmosphere

2.2: 4 h / 0 - 20 °C / Inert atmosphere

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1016/j.tetlet.2018.03.062