3,3'-Bi[1,2,3]triazolo[1,5-a]pyridine

Base Information

• Chemical Name: 3,3'-Bi[1,2,3]triazolo[1,5-a]pyridine
• CAS No.: 59742-90-4
• Molecular Formula: C12H8 N6
• Molecular Weight: 236.2321
• NSC Number: 196160
• DSSTox Substance ID: DTXSID60307880
• Nikkaji Number: J1.284.542A
• Wikidata: Q82055465
• Mol file: 59742-90-4.mol

Synonyms:3,3'-bi[1,2,3]triazolo[1,5-a]pyridine;59742-90-4;NSC196160;DTXSID60307880;NSC-196160

Chemical Property of 3,3'-Bi[1,2,3]triazolo[1,5-a]pyridine

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 236.08104428
• Heavy Atom Count: 18
• Complexity: 281

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(N=NN2C=C1)C3=C4C=CC=CN4N=N3

Technology Process of 3,3'-Bi[1,2,3]triazolo[1,5-a]pyridine

There total 7 articles about 3,3'-Bi[1,2,3]triazolo[1,5-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

3-iodo-[1,2,3]triazolo[1,5-a]pyridine (916756-21-3) + m-tolylboronic acid (17933-03-8) → 3-m-tolyl-[1,2,3]triazolo[1,5-a]pyridine + 3,3'-bi[1,2,3]triazolo[1,5-α]pyridine (59742-90-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; at 85 ℃; for 20h;

DOI:10.1016/j.tetlet.2006.09.051

Reference yield: 76.0%

3-iodo-[1,2,3]triazolo[1,5-a]pyridine (916756-21-3) + 4-methoxyphenylboronic acid (5720-07-0) → 3,3'-bi[1,2,3]triazolo[1,5-α]pyridine (59742-90-4) + 3-(4-methoxyphenyl)-[l,2,3]triazolo[1,5-a]pyridine (78539-92-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; at 85 ℃; for 20h;

DOI:10.1016/j.tetlet.2006.09.051

Reference yield: 68.0%

3-iodo-[1,2,3]triazolo[1,5-a]pyridine (916756-21-3) + 4-Bromophenylboronic acid (5467-74-3) → 3-(4-bromo-phenyl)-[1,2,3]triazolo[1,5-a]pyridine + 3,3'-bi[1,2,3]triazolo[1,5-α]pyridine (59742-90-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; at 85 ℃; for 18h;

DOI:10.1016/j.tetlet.2006.09.051

upstream raw materials:

2,2'-Pyridil

3-iodo-[1,2,3]triazolo[1,5-a]pyridine

2-Methylphenylboronic acid

m-tolylboronic acid