(S)-Methyl 3-amino-4-methylpentanoate hydrochloride

Base Information

• Chemical Name: (S)-Methyl 3-amino-4-methylpentanoate hydrochloride
• CAS No.: 679789-35-6
• Molecular Formula: C₇H₁₅NO₂*ClH
• Molecular Weight: 181.663
• European Community (EC) Number: 859-773-5

Synonyms:679789-35-6;(S)-Methyl 3-amino-4-methylpentanoate hydrochloride;METHYL (S)-HOMO-BETA-VALINATE HCL;(S)-3-Amino-4-methyl-pentanoic acid methyl ester, HCl;(S)-3-Amino-4-methyl-pentanoic acid methyl ester hydrochloride;MFCD12068618;Pentanoic acid, 3-amino-4-methyl-, methyl ester, hydrochloride, (3S)-;AS-40286;Methyl (S)-homo-beta-valinate hydrochloride;CS-0171932;EN300-1663097;(S)-Methyl3-amino-4-methylpentanoatehydrochloride;A915475;Methyl(S)-3-amino-4-methylpentanoatehydrochloride;methyl (3S)-3-amino-4-methylpentanoate;hydrochloride;METHYL (3S)-3-AMINO-4-METHYLPENTANOATE HYDROCHLORIDE

Chemical Property of (S)-Methyl 3-amino-4-methylpentanoate hydrochloride

Chemical Property:

• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 181.0869564
• Heavy Atom Count: 11
• Complexity: 112

Purity/Quality:

97% ^*data from raw suppliers

Methyl(S)-homo-β-ValinateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)C(CC(=O)OC)N.Cl
• Isomeric SMILES: CC(C)[C@H](CC(=O)OC)N.Cl

Technology Process of (S)-Methyl 3-amino-4-methylpentanoate hydrochloride

There total 3 articles about (S)-Methyl 3-amino-4-methylpentanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methanol (67-56-1) + (3S)-3-amino-4-methylpentanoic acid → (S)-homo-β-Val-OMe hydrochloride (679789-35-6,172823-13-1)

Guidance literature:

With thionyl chloride; at 0 - 23 ℃; for 16h; Inert atmosphere;

DOI:10.1021/np500925y

Reference yield: 4.0%

methyl 3-amino-4-methylpentanoate hydrochloride (172823-13-1) + malonic acid dimethyl ester (108-59-8) → (S)-homo-β-Val-OMe hydrochloride (679789-35-6,172823-13-1) + C11H19NO5 (1219839-51-6) + (3R)-3-amino-4-methyl-pentanoic acid methyl ester hydrochloride (172823-13-1)

Guidance literature:

methyl 3-amino-4-methylpentanoate hydrochloride; malonic acid dimethyl ester; With triethylamine; In 1,4-dioxane; at 20 ℃; for 120h; Inert atmosphere; Enzymatic reaction;

With hydrogenchloride; In 1,4-dioxane; water; ethyl acetate; optical yield given as %ee; enantioselective reaction;

DOI:10.1016/j.tetasy.2009.12.021

Reference yield:

(RS,S)-(-)-methyl N-(tert-butanesulfinyl)-3-amino-4-methylpentanoate → (S)-homo-β-Val-OMe hydrochloride (679789-35-6,172823-13-1)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/jo900353p

upstream raw materials:

methyl 3-amino-4-methylpentanoate hydrochloride

malonic acid dimethyl ester

methanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 679789-35-6 (S)-homo-β-Val-OMe hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send