Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-methyl-5-phenyl-, ethyl ester

Base Information

Chemical Name:Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-methyl-5-phenyl-, ethyl ester
CAS No.:140706-36-1
Molecular Formula:C16H15N3O2
Molecular Weight:281.30900
Hs Code.:
Mol file:140706-36-1.mol

Synonyms:7-Methyl-5-phenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester;

Suppliers and Price of Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-methyl-5-phenyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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American Custom Chemicals Corporation
7-METHYL-5-PHENYL-PYRAZOLO(1,5-A)PYRIMIDINE-3-CARBOXYLIC ACID ETHYL ESTER 95.00%
5MG
$ 499.15

Total 0 raw suppliers

Chemical Property of Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-methyl-5-phenyl-, ethyl ester

Chemical Property:

PSA：56.49000
LogP:2.88140

Purity/Quality:: 7-METHYL-5-PHENYL-PYRAZOLO(1,5-A)PYRIMIDINE-3-CARBOXYLIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

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Technology Process of Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-methyl-5-phenyl-, ethyl ester

There total 2 articles about Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-methyl-5-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 6994-25-8,103259-35-4,19750-02-8
3-amino-4-pyrazolecarboxylic acid ethyl ester

: 93-91-4
1-phenylbutan-1,3-dione

: 140706-36-1
ethyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylate

: 140706-33-8
ethyl 5-methyl-7-phenylpyrazolo<1,5-a>pyrimidine-3-carboxylate

Guidance literature:: With acetic acid; at 110 ℃;
DOI:10.1021/jm300063b

Reference yield: 15.0%

: 1260243-04-6,6994-25-8
ethyl 5-amino-1H-pyrazole-4-carboxylate

: 93-91-4
1-phenylbutan-1,3-dione

: 140706-36-1
ethyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylate

: 140706-33-8
ethyl 5-methyl-7-phenylpyrazolo<1,5-a>pyrimidine-3-carboxylate

Guidance literature:: With acetic acid; for 4h; Reflux;
DOI:10.1016/j.bmc.2010.10.035

Reference yield: 96.0%

: 140706-36-1
ethyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylate

: ethyl 7-methyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate

Guidance literature:: ethyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylate; With sodium tetrahydroborate; In methanol; at 20 ℃; for 5h;

With citric acid; In methanol; diastereoselective reaction; Saturated solution;
DOI:10.1016/j.bmc.2010.10.035