(4-Nitro-phenyl)-p-tolyl-methanone

Base Information

• Chemical Name: (4-Nitro-phenyl)-p-tolyl-methanone
• CAS No.: 5350-47-0
• Molecular Formula: C14H11 N O3
• Molecular Weight: 241.246
• Mol file: 5350-47-0.mol

Synonyms:Benzophenone, 4-methyl-4'-nitro- (7CI,8CI);4-Methyl-4'-nitrobenzophenone; 4-Nitro-4'-methylbenzophenone; 4-Nitrobenzoyl-4-methylbenzene;NSC 32

Chemical Property of (4-Nitro-phenyl)-p-tolyl-methanone

Chemical Property:

• Vapor Pressure: 3.53E-07mmHg at 25°C
• Melting Point: 124°C
• Refractive Index: 1.5780 (estimate)
• Boiling Point: 417.5°Cat760mmHg
• Flash Point: 203.1°C
• PSA: 62.89000
• Density: 1.232g/cm³
• LogP: 3.65740

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-Nitro-phenyl)-p-tolyl-methanone

There total 40 articles about (4-Nitro-phenyl)-p-tolyl-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

tri(p-tolyl)bismuth (5142-75-6) + 4-nitro-benzoyl chloride (122-04-3) → (4-methylphenyl)(4-nitrophenyl)methanone (5350-47-0)

Guidance literature:

With tributyl-amine; In 1-methyl-pyrrolidin-2-one; at 80 ℃; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejoc.201201432

Reference yield: 92.0%

p-nitrobenzene iodide (636-98-6) + carbon monoxide (201230-82-2) + 4-methylphenylboronic acid (5720-05-8) → (4-methylphenyl)(4-nitrophenyl)methanone (5350-47-0)

Guidance literature:

With potassium fluoride; potassium phosphate; copper; Trimethylacetic acid; at 100 ℃; for 9h; under 760.051 Torr;

DOI:10.1039/c4ra08594a

Reference yield: 90.0%

toluene (108-88-3,15644-74-3,16713-13-6) + 4-nitro-benzoic acid (62-23-7) → (4-methylphenyl)(4-nitrophenyl)methanone (5350-47-0)

Guidance literature:

With cross-linked polystyrene-supported aluminum triflate; at 80 ℃; for 3.1h; regioselective reaction; Neat (no solvent);

DOI:10.2298/JSC100215010P

upstream raw materials:

toluene

4-nitro-benzoic acid

p-nitrobenzene iodide

carbon monoxide