(Trimethylsilyl)octyl ether

Base Information

• Chemical Name: (Trimethylsilyl)octyl ether
• CAS No.: 14246-16-3
• Molecular Formula: C11H26OSi
• Molecular Weight: 202.412
• Hs Code.: 2931900090
• Mol file: 14246-16-3.mol

Synonyms:n-C8H17OSiMe3;n-octyl trimethylsilyl ether;n-C8H17OTMS;trimethylsilyl n-octyl ether;Octyl trimethylsilyl ether;

Chemical Property of (Trimethylsilyl)octyl ether

Chemical Property:

• PSA: 9.23000
• LogP: 4.19840

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (Trimethylsilyl)octyl ether

There total 10 articles about (Trimethylsilyl)octyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

octanol (111-87-5) + allyl-trimethyl-silane (762-72-1) → propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) + trimethyl(oct-1-yloxy)silane (14246-16-3)

Guidance literature:

iodine; In chloroform; at 40 ℃; for 1h; other allylsilane;

DOI:10.1246/cl.1981.85

Reference yield: 67.0%

octanol (111-87-5) + trimethylsilanyl-acetic acid ethyl ester (4071-88-9) → trimethyl(oct-1-yloxy)silane (14246-16-3) + (Z)-1-phenyl-2-(trimethylsiloxy)propene (19980-24-6)

Guidance literature:

With tetrabutylammonium fluoride absorbed on silica gel; In tetrahydrofuran; for 8.5h; Ambient temperature;

Reference yield:

1-(trimethylsilyl)piperidin-2-one (3553-93-3) + octanol (111-87-5) → piperidin-2-one (675-20-7) + trimethyl(oct-1-yloxy)silane (14246-16-3)

Guidance literature:

In tetrahydrofuran; at 20 ℃; Kinetics;

DOI:10.1016/j.tetlet.2017.04.057

upstream raw materials:

methyl magnesium iodide

n-octyl cyclohexyl ether

octanol

trimethylsilanyl-acetic acid ethyl ester

Downstream raw materials:

2-octyloxy-tetrahydro-pyran

Mesitol

octanol

1-bromo-octane

Refernces

• 1、 Khusainova,Khafizova,Tyumkina,Dzhemilev. "Synthesis of 1-fluoro-2-alkylboriranes by the reaction of α-olefins with BF3·THF catalyzed by Cp2TiCl2". . p. 1438 - 1441. Retrieved 2016/08/10.
• 2、 Moghadam, Majid,Tangestaninejad, Shahram,Mirkhani, Valiollah,Mohammadpoor-Baltork, Iraj,Gharaati, Shadab. "[SnIV(TPP)(BF4)2]: An efficient and reusable catalyst for chemoselective trimethylsilylation of alcohols and phenols with hexamethyldisilazane". experimental part. p. 212 - 219. Retrieved 2010/04/04.