N-decanoylglycine

Base Information

• Chemical Name: N-decanoylglycine
• CAS No.: 14305-32-9
• Molecular Formula: C12H23NO3
• Molecular Weight: 229.32
• DSSTox Substance ID: DTXSID601314674
• Nikkaji Number: J846.169D
• Wikidata: Q27144666
• Metabolomics Workbench ID: 42276
• ChEMBL ID: CHEMBL3221595
• Mol file: 14305-32-9.mol

Synonyms:N-decanoylglycine;Decanoylglycine;2-(decanoylamino)acetic Acid;14305-32-9;decyl glycine;acylglycine c:10;CHEBI:74430;caprylglycine;2-decanamidoacetic acid;starbld0024329;N-(1-Oxodecyl)glycine;SCHEMBL343029;CHEMBL3221595;DTXSID601314674;AKOS009363716;HY-131173;CS-0130022;N-Decanoylglycine, analytical reference material;SR-01000196133;SR-01000196133-1;Q27144666

Chemical Property of N-decanoylglycine

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 10
• Exact Mass: 229.16779360
• Heavy Atom Count: 16
• Complexity: 204

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCCCCC(=O)NCC(=O)O

Technology Process of N-decanoylglycine

There total 1 articles about N-decanoylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(palmitoylamino)ethanol (544-31-0) + N-stearoylethanolamine (111-57-9,8038-89-9) + N-(2-hydroxyethyl)dodecanamide (142-78-9) + myristic monoethanolamide (142-58-5) + N‐(2‐hydroxyethyl)octanamide (7112-02-9) + decanoic acid monoethanolamide (7726-08-1) → N-dodecanoylglycine (7596-88-5) + N-myristoylglycine (14246-55-0) + N-palmitoyl glycine (2441-41-0) + N-stearoylglycine (6333-54-6) + N-n-decanoylglycine (14305-32-9) + N-(1-oxooctyl)glycine (14246-53-8)

Guidance literature:

2-(palmitoylamino)ethanol; N-stearoylethanolamine; N-(2-hydroxyethyl)dodecanamide; myristic monoethanolamide; N‐(2‐hydroxyethyl)octanamide; decanoic acid monoethanolamide; With sodium hydroxide; sodium hypochlorite; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; potassium bromide; In water; toluene; at 31 - 38 ℃; for 5 - 6h; pH=6.9 - 8.9;

With hydrogenchloride; In tetrahydrofuran; water; toluene; pH=2.2; Product distribution / selectivity;

Reference yield: 41.0%

4-formylphenyl acetate (878-00-2) + N-n-decanoylglycine (14305-32-9) → (Z)-4-((2-nonyl-5-oxooxazol-4(5H)-ylidene)methyl)phenyl acetate

Guidance literature:

N-n-decanoylglycine; With sodium acetate; acetic anhydride; In tetrahydrofuran; at 65 ℃; for 0.75h;

4-formylphenyl acetate; In tetrahydrofuran; at 65 ℃; for 24h;

DOI:10.1021/acs.jnatprod.9b00028

upstream raw materials:

2-(palmitoylamino)ethanol

N-stearoylethanolamine

N-(2-hydroxyethyl)dodecanamide

myristic monoethanolamide