Benzene, 2-ethenyl-1,4-dimethoxy-

Base Information

• Chemical Name: Benzene, 2-ethenyl-1,4-dimethoxy-
• CAS No.: 14568-68-4
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• ChEMBL ID: CHEMBL3415520
• DSSTox Substance ID: DTXSID60469679
• Nikkaji Number: J753.951G
• Wikidata: Q82297500
• Mol file: 14568-68-4.mol

Synonyms:Benzene, 2-ethenyl-1,4-dimethoxy-;14568-68-4;2-ETHENYL-1,4-DIMETHOXYBENZENE;2,5-dimethoxystyrene;SCHEMBL1792533;CHEMBL3415520;DTXSID60469679;Benzene,2-ethenyl-1,4-dimethoxy-;AKOS013991240;BS-48765;CS-0162772;F18407;EN300-1243647;ETHYL2,4-DIPHENYLIMIDAZOLE-5-CARBOXYLATE

Chemical Property of Benzene, 2-ethenyl-1,4-dimethoxy-

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 164.083729621
• Heavy Atom Count: 12
• Complexity: 145

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1)OC)C=C

Technology Process of Benzene, 2-ethenyl-1,4-dimethoxy-

There total 9 articles about Benzene, 2-ethenyl-1,4-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

Methyltriphenylphosphonium bromide (1779-49-3) + 2,5-dimethoxybenzaldehyde (93-02-7) → 1,4-dimethoxy-2-vinylbenzene (14568-68-4)

Guidance literature:

Methyltriphenylphosphonium bromide; With sodium amide; In diethyl ether; at 20 ℃; for 10h; Inert atmosphere;

2,5-dimethoxybenzaldehyde; In diethyl ether; at -10 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2010.05.042

Reference yield: 48.0%

1-(2,5-bis(methoxy)phenyl)ethan-1-ol (41038-40-8,89691-64-5,120523-13-9) → 1,4-dimethoxy-2-vinylbenzene (14568-68-4)

Guidance literature:

With toluene-4-sulfonic acid; In chloroform; for 8h;

DOI:10.1080/00397910701319189

Reference yield: 42.0%

1-(2,5-Dimethoxyphenyl)-2-tosyloxyethane (155639-44-4) → 1,4-dimethoxy-2-vinylbenzene (14568-68-4) + 2-(2-fluoroethyl)-1,4-dimethoxybenzene

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 40 ℃; for 24h; under 750.06 Torr;

DOI:10.1016/0022-1139(96)03417-3

upstream raw materials:

1-(2,5-bis(methoxy)phenyl)ethan-1-ol

1-(2,5-Dimethoxyphenyl)-2-tosyloxyethane

2-(2,5-dimethoxyphenyl)ethanol

2,5-dimethoxyphenylacetyl chloride

Downstream raw materials:

8-(2,5-dimethoxy-phenyl)-7,10-diphenyl-8,9-dihydro-fluoranthene

(2,5-dimethoxyphenyl)ethylene glycol

2,5-dimethoxy-4'-amino-trans-stilbene