3,4-Dimethyl-5-phenyl-2(3H)-oxazolimine

Base Information

• Chemical Name: 3,4-Dimethyl-5-phenyl-2(3H)-oxazolimine
• CAS No.: 49656-79-3
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.229
• DSSTox Substance ID: DTXSID301278100
• Mol file: 49656-79-3.mol

Synonyms:3,4-Dimethyl-5-phenyl-2(3H)-oxazolimine;DTXSID301278100;49656-79-3

Chemical Property of 3,4-Dimethyl-5-phenyl-2(3H)-oxazolimine

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 188.094963011
• Heavy Atom Count: 14
• Complexity: 277

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(OC(=N)N1C)C2=CC=CC=C2

Technology Process of 3,4-Dimethyl-5-phenyl-2(3H)-oxazolimine

There total 2 articles about 3,4-Dimethyl-5-phenyl-2(3H)-oxazolimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromocyane (506-68-3) + 2-methylamino-1-phenyl-1-propanone hydrochloride (49656-78-2) → 3,4-dimethyl-5-phenyl-3H-oxazol-2-ylideneamine (49656-79-3)

Guidance literature:

Multistep reaction; (i) aq. NaOH, Et₂O, (ii) /BRN= 1697296/;

Reference yield:

→ 3,4-dimethyl-5-phenyl-3H-oxazol-2-ylideneamine (49656-79-3)

Guidance literature:

α-Methylaminopropiophenon*HCl, BrCN;

Reference yield:

3,4-dimethyl-5-phenyl-3H-oxazol-2-ylideneamine (49656-79-3) + propionyl chloride (79-03-8) → N-(3,4-dimethyl-5-phenyl-3H-oxazol-2-ylidene)-propionamide (52597-05-4)

Guidance literature:

In xylene; for 3h; Heating;

upstream raw materials:

bromocyane

2-methylamino-1-phenyl-1-propanone hydrochloride

Downstream raw materials:

N-(3,4-dimethyl-5-phenyl-3H-oxazol-2-ylidene)-propionamide

N-(3,4-dimethyl-5-phenyl-3H-oxazol-2-ylidene)-acetamide